The Preventive Effect of Urinary Trypsin Inhibitor on Postoperative Cognitive Dysfunction, on the Aspect of Behavior, Evaluated by Y-Maze Test, via Modulation of Microglial Activity

This experimental study was designed to evaluate the effect of ulinastatin, a urinary trypsin inhibitor, on postoperative cognitive dysfunction (POCD) in rats under general anesthesia with isoflurane, on the aspect of behavior, as evaluated using a Y-maze test and focusing on microglial activity. Ul...

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Veröffentlicht in:	International journal of molecular sciences 2024-02, Vol.25 (5), p.2708
Hauptverfasser:	Cho, Eun-Hwa, In, Chi-Bum, Lee, Gyu-Won, Hong, Seung-Wan, Seo, Eun-Hye, Lee, Won Hyung, Kim, Seong-Hyop
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Behavior Cognition disorders Cognitive ability Cytokines Disease prevention General anesthesia Genotype & phenotype Inflammation Nervous system Neurons Quality of life Surgery Trypsin Tumor necrosis factor-TNF
Online-Zugang:	Volltext
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