Advantages of Using 3D Spheroid Culture Systems in Toxicological and Pharmacological Assessment for Osteogenesis Research

Bone differentiation is crucial for skeletal development and maintenance. Its dysfunction can cause various pathological conditions such as rickets, osteoporosis, osteogenesis imperfecta, or Paget's disease. Although traditional two-dimensional cell culture systems have contributed significantl...

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Veröffentlicht in:	International journal of molecular sciences 2024-02, Vol.25 (5), p.2512
Hauptverfasser:	Yun, Chawon, Kim, Sou Hyun, Kim, Kyung Mok, Yang, Min Hye, Byun, Mi Ran, Kim, Joung-Hee, Kwon, Doyoung, Pham, Huyen T M, Kim, Hyo-Sop, Kim, Jae-Ho, Jung, Young-Suk
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology Biomedical research Bones Cancer research Cell culture Development and progression Disease Drug development Drug testing Extracellular matrix Gene expression Growth factors Medical research Osteoporosis Physiology Precision medicine Regenerative medicine Review Spheroids Tissue engineering Toxicity Tumors
Online-Zugang:	Volltext
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