Probing Activation and Conformational Dynamics of the Vesicle-Reconstituted β2 Adrenergic Receptor at the Single-Molecule Level

G-protein-coupled receptors (GPCRs) are structurally flexible membrane proteins that mediate a host of physiological responses to extracellular ligands like hormones and neurotransmitters. Fine features of their dynamic structural behavior are hypothesized to encode the functional plasticity seen in...

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Veröffentlicht in:	The journal of physical chemistry. B 2024-03, Vol.128 (9), p.2124-2133
Hauptverfasser:	Tutkus, Marijonas, Lundgaard, Christian V., Veshaguri, Salome, Tønnesen, Asger, Hatzakis, Nikos, Rasmussen, Søren G. F., Stamou, Dimitrios
Format:	Artikel
Sprache:	eng
Schlagworte:	B: Biophysical and Biochemical Systems and Processes
Online-Zugang:	Volltext
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