Chronic oxytocin-driven alternative splicing of Crfr2α induces anxiety

The neuropeptide oxytocin (OXT) has generated considerable interest as potential treatment for psychiatric disorders, including anxiety and autism spectrum disorders. However, the behavioral and molecular consequences associated with chronic OXT treatment and chronic receptor (OXTR) activation have...

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Veröffentlicht in:	Molecular psychiatry 2023-11, Vol.28 (11), p.4742-4755
Hauptverfasser:	Winter, Julia, Meyer, Magdalena, Berger, Ilona, Royer, Melanie, Bianchi, Marta, Kuffner, Kerstin, Peters, Sebastian, Stang, Simone, Langgartner, Dominik, Hartmann, Finn, Schmidtner, Anna K., Reber, Stefan O., Bosch, Oliver J., Bludau, Anna, Slattery, David A., van den Burg, Erwin H., Jurek, Benjamin, Neumann, Inga D.
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/1 13/51 13/89 14 14/32 14/63 38 38/77 45 45/15 45/90 59 631/1647 631/337 631/378 631/45 631/80 64 82 82/80 Alternative splicing Anxiety Autism Behavior Behavioral Sciences Biological Psychology Cerebrospinal fluid Corticotropin-releasing hormone Hormones Hypothalamus Intracellular signalling Medicine Medicine & Public Health Mental disorders Neurosciences Oxytocin Pharmacotherapy Psychiatry Signal transduction
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