A PilZ domain protein interacts with the transcriptional regulator HinK to regulate type VI secretion system in Pseudomonas aeruginosa

Type VI secretion systems (T6SS) are bacterial macromolecular complexes that secrete effectors into target cells or the extracellular environment, leading to the demise of adjacent cells and providing a survival advantage. Although studies have shown that the T6SS in Pseudomonas aeruginosa is regula...

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Veröffentlicht in:	The Journal of biological chemistry 2024-03, Vol.300 (3), p.105741-105741, Article 105741
Hauptverfasser:	Cheng, Tianfang, Cheang, Qing Wei, Xu, Linghui, Sheng, Shuo, Li, Zhaoting, Shi, Yu, Zhang, Huiyan, Pang, Li Mei, Liu, Ding Xiang, Yang, Liang, Liang, Zhao-Xun, Wang, Junxia
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism c-di-GMP Cyclic GMP - analogs & derivatives Cyclic GMP - metabolism Electrophoretic Mobility Shift Assay Gene Expression Regulation, Bacterial HinK Immunoprecipitation Mutation PilZ PqsR Promoter Regions, Genetic Protein Binding Pseudomonas aeruginosa Pseudomonas aeruginosa - genetics Pseudomonas aeruginosa - metabolism Pyocyanine - metabolism Quorum Sensing Second Messenger Systems Transcription, Genetic TssZ Two-Hybrid System Techniques Type VI Secretion Systems - genetics Type VI Secretion Systems - metabolism
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