Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation
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Veröffentlicht in: | Molecular and Cellular Biology 1998-09, Vol.18 (9), p.5208-5218 |
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container_title | Molecular and Cellular Biology |
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creator | Gale, Michael Blakely, Collin M. Kwieciszewski, Bart Tan, Seng-Lai Dossett, Michelle Tang, Norina M. Korth, Marcus J. Polyak, Stephen J. Gretch, David R. Katze, Michael G. |
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</description><identifier>ISSN: 0270-7306</identifier><identifier>ISSN: 1098-5549</identifier><identifier>EISSN: 1098-5549</identifier><identifier>DOI: 10.1128/mcb.18.9.5208</identifier><identifier>PMID: 9710605</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Animals ; Base Sequence ; Binding Sites ; Cloning, Molecular ; COS Cells ; Dimerization ; DNA Primers ; eIF-2 Kinase - chemistry ; eIF-2 Kinase - metabolism ; Escherichia coli ; Gene Expression ; Gene Expression Regulation, Enzymologic ; Hepacivirus - drug effects ; Hepacivirus - pathogenicity ; Hepacivirus - physiology ; Hepatitis C virus ; Interferons - pharmacology ; Models, Biological ; Molecular Sequence Data ; Mutagenesis, Site-Directed ; Point Mutation ; Polymerase Chain Reaction ; Recombinant Proteins - biosynthesis ; Recombinant Proteins - chemistry ; Recombinant Proteins - metabolism ; RNA-Dependent RNA Polymerase - metabolism ; Sequence Deletion ; Transfection ; Viral Nonstructural Proteins - biosynthesis ; Viral Nonstructural Proteins - chemistry ; Viral Nonstructural Proteins - metabolism ; Virus Replication</subject><ispartof>Molecular and Cellular Biology, 1998-09, Vol.18 (9), p.5208-5218</ispartof><rights>Copyright © 1998 American Society for Microbiology 1998</rights><rights>Copyright © 1998, American Society for Microbiology 1998</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c555t-34e4fa9c3dffa5ca60dfd894608018e04fdeda44c19dcdb24b10d30dc6f5b3673</citedby><cites>FETCH-LOGICAL-c555t-34e4fa9c3dffa5ca60dfd894608018e04fdeda44c19dcdb24b10d30dc6f5b3673</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC109106/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC109106/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9710605$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gale, Michael</creatorcontrib><creatorcontrib>Blakely, Collin M.</creatorcontrib><creatorcontrib>Kwieciszewski, Bart</creatorcontrib><creatorcontrib>Tan, Seng-Lai</creatorcontrib><creatorcontrib>Dossett, Michelle</creatorcontrib><creatorcontrib>Tang, Norina M.</creatorcontrib><creatorcontrib>Korth, Marcus J.</creatorcontrib><creatorcontrib>Polyak, Stephen J.</creatorcontrib><creatorcontrib>Gretch, David R.</creatorcontrib><creatorcontrib>Katze, Michael G.</creatorcontrib><title>Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation</title><title>Molecular and Cellular Biology</title><addtitle>Mol Cell Biol</addtitle><description>Article Usage Stats
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</description><subject>Animals</subject><subject>Base Sequence</subject><subject>Binding Sites</subject><subject>Cloning, Molecular</subject><subject>COS Cells</subject><subject>Dimerization</subject><subject>DNA Primers</subject><subject>eIF-2 Kinase - chemistry</subject><subject>eIF-2 Kinase - metabolism</subject><subject>Escherichia coli</subject><subject>Gene Expression</subject><subject>Gene Expression Regulation, Enzymologic</subject><subject>Hepacivirus - drug effects</subject><subject>Hepacivirus - pathogenicity</subject><subject>Hepacivirus - physiology</subject><subject>Hepatitis C virus</subject><subject>Interferons - pharmacology</subject><subject>Models, Biological</subject><subject>Molecular Sequence Data</subject><subject>Mutagenesis, Site-Directed</subject><subject>Point Mutation</subject><subject>Polymerase Chain Reaction</subject><subject>Recombinant Proteins - biosynthesis</subject><subject>Recombinant Proteins - chemistry</subject><subject>Recombinant Proteins - metabolism</subject><subject>RNA-Dependent RNA Polymerase - metabolism</subject><subject>Sequence Deletion</subject><subject>Transfection</subject><subject>Viral Nonstructural Proteins - biosynthesis</subject><subject>Viral Nonstructural Proteins - chemistry</subject><subject>Viral Nonstructural Proteins - metabolism</subject><subject>Virus Replication</subject><issn>0270-7306</issn><issn>1098-5549</issn><issn>1098-5549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1ks1vEzEUxC0EKmnhyBHJXLhteM6unTUSh7KiFLWBqgKultcfiZHXDra3Vf57NkqoyoGTD_Obsd8bI_SKwJyQRftuUP2ctHM-pwton6AZAd5WlDb8KZrBYgnVsgb2HJ3m_AsAGIf6BJ3wJQEGdIbuuhhKih5Hi2-ubvFNisW4gK9ckNngfocvzVYWV1zGHf7p0pjx1xhySaMqY5Ie0_O_pvd4Fb1Ro5cJr4zayODykPfJx7Rbs57E4mJ4gZ5Z6bN5eTzP0I-LT9-7y-r62-cv3fl1pSilpaob01jJVa2tlVRJBtrqljcMWiCtgcZqo2XTKMK10v2i6QnoGrRilvY1W9Zn6MMhdzv2g9HKTMNKL7bJDTLtRJRO_KsEtxHreCemLU4bmvxvj_4Uf48mFzG4rIz3Mpg4ZkEYpYxxMoHVAVQp5pyMfbiDgNj3JFbdR0FawcW-p4l__fhhD_SxmElvD7oLNqZB3sfktShy52OySQblsqj_F_3mYN249ebeJSNkHsT0TR4xfwBB_q82</recordid><startdate>19980901</startdate><enddate>19980901</enddate><creator>Gale, Michael</creator><creator>Blakely, Collin M.</creator><creator>Kwieciszewski, Bart</creator><creator>Tan, Seng-Lai</creator><creator>Dossett, Michelle</creator><creator>Tang, Norina M.</creator><creator>Korth, Marcus J.</creator><creator>Polyak, Stephen J.</creator><creator>Gretch, David R.</creator><creator>Katze, Michael G.</creator><general>American Society for Microbiology</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TM</scope><scope>7U9</scope><scope>H94</scope><scope>5PM</scope></search><sort><creationdate>19980901</creationdate><title>Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation</title><author>Gale, Michael ; Blakely, Collin M. ; Kwieciszewski, Bart ; Tan, Seng-Lai ; Dossett, Michelle ; Tang, Norina M. ; Korth, Marcus J. ; Polyak, Stephen J. ; Gretch, David R. ; Katze, Michael G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c555t-34e4fa9c3dffa5ca60dfd894608018e04fdeda44c19dcdb24b10d30dc6f5b3673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Animals</topic><topic>Base Sequence</topic><topic>Binding Sites</topic><topic>Cloning, Molecular</topic><topic>COS Cells</topic><topic>Dimerization</topic><topic>DNA Primers</topic><topic>eIF-2 Kinase - chemistry</topic><topic>eIF-2 Kinase - metabolism</topic><topic>Escherichia coli</topic><topic>Gene Expression</topic><topic>Gene Expression Regulation, Enzymologic</topic><topic>Hepacivirus - drug effects</topic><topic>Hepacivirus - pathogenicity</topic><topic>Hepacivirus - physiology</topic><topic>Hepatitis C virus</topic><topic>Interferons - pharmacology</topic><topic>Models, Biological</topic><topic>Molecular Sequence Data</topic><topic>Mutagenesis, Site-Directed</topic><topic>Point Mutation</topic><topic>Polymerase Chain Reaction</topic><topic>Recombinant Proteins - biosynthesis</topic><topic>Recombinant Proteins - chemistry</topic><topic>Recombinant Proteins - metabolism</topic><topic>RNA-Dependent RNA Polymerase - metabolism</topic><topic>Sequence Deletion</topic><topic>Transfection</topic><topic>Viral Nonstructural Proteins - biosynthesis</topic><topic>Viral Nonstructural Proteins - chemistry</topic><topic>Viral Nonstructural Proteins - metabolism</topic><topic>Virus Replication</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gale, Michael</creatorcontrib><creatorcontrib>Blakely, Collin M.</creatorcontrib><creatorcontrib>Kwieciszewski, Bart</creatorcontrib><creatorcontrib>Tan, Seng-Lai</creatorcontrib><creatorcontrib>Dossett, Michelle</creatorcontrib><creatorcontrib>Tang, Norina M.</creatorcontrib><creatorcontrib>Korth, Marcus J.</creatorcontrib><creatorcontrib>Polyak, Stephen J.</creatorcontrib><creatorcontrib>Gretch, David R.</creatorcontrib><creatorcontrib>Katze, Michael G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Molecular and Cellular Biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gale, Michael</au><au>Blakely, Collin M.</au><au>Kwieciszewski, Bart</au><au>Tan, Seng-Lai</au><au>Dossett, Michelle</au><au>Tang, Norina M.</au><au>Korth, Marcus J.</au><au>Polyak, Stephen J.</au><au>Gretch, David R.</au><au>Katze, Michael G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation</atitle><jtitle>Molecular and Cellular Biology</jtitle><addtitle>Mol Cell Biol</addtitle><date>1998-09-01</date><risdate>1998</risdate><volume>18</volume><issue>9</issue><spage>5208</spage><epage>5218</epage><pages>5208-5218</pages><issn>0270-7306</issn><issn>1098-5549</issn><eissn>1098-5549</eissn><abstract>Article Usage Stats
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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>9710605</pmid><doi>10.1128/mcb.18.9.5208</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Animals Base Sequence Binding Sites Cloning, Molecular COS Cells Dimerization DNA Primers eIF-2 Kinase - chemistry eIF-2 Kinase - metabolism Escherichia coli Gene Expression Gene Expression Regulation, Enzymologic Hepacivirus - drug effects Hepacivirus - pathogenicity Hepacivirus - physiology Hepatitis C virus Interferons - pharmacology Models, Biological Molecular Sequence Data Mutagenesis, Site-Directed Point Mutation Polymerase Chain Reaction Recombinant Proteins - biosynthesis Recombinant Proteins - chemistry Recombinant Proteins - metabolism RNA-Dependent RNA Polymerase - metabolism Sequence Deletion Transfection Viral Nonstructural Proteins - biosynthesis Viral Nonstructural Proteins - chemistry Viral Nonstructural Proteins - metabolism Virus Replication |
title | Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation |
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