Cell-specific alterations in autophagy-lysosomal activity near the chronically implanted microelectrodes

Intracortical microelectrodes that can record and stimulate brain activity have become a valuable technique for basic science research and clinical applications. However, long-term implantation of these microelectrodes can lead to progressive neurodegeneration in the surrounding microenvironment, ch...

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Veröffentlicht in:	Biomaterials 2023-11, Vol.302, p.122316-122316, Article 122316
Hauptverfasser:	Chen, Keying, Garcia Padilla, Camila, Kiselyov, Kirill, Kozai, Takashi D.Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy - physiology Brain Injuries brain metabolism Brain-computer interface Electrodes, Implanted - adverse effects Glial reactivity Humans Lysosomes Microelectrodes Neurodegenerative Diseases Neuron survival Tissue homeostasis
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