Identification of C4BPA as biomarker associated with immune infiltration and prognosis in breast cancer
is a gene that encodes the C4BP protein α chain and is involved in the complement system. is regarded as a new biomarker for cancer, especially for non-small cell lung cancer and ovarian cancer. However, its role in breast cancer (BC) has not yet been determined. In this research, we used a bioinfor...
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Veröffentlicht in: | Translational cancer research 2024-01, Vol.13 (1), p.25-45 |
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Sprache: | eng |
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Zusammenfassung: | is a gene that encodes the C4BP protein α chain and is involved in the complement system.
is regarded as a new biomarker for cancer, especially for non-small cell lung cancer and ovarian cancer. However, its role in breast cancer (BC) has not yet been determined.
In this research, we used a bioinformatics approach to assess the prognostic significance of C4BPA in BC. Utilizing a variety of databases and analysis tools, including The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx), Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), R, STRING, and the Kaplan-Meier plotter, we specifically assessed the connection between C4BPA and BC.
expression was markedly decreased in BC tissues compared to its expression in normal breast tissues (P |
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ISSN: | 2218-676X 2219-6803 |
DOI: | 10.21037/tcr-23-1215 |