Relationship and Accuracy of Urine Lead as an Alternative to Blood Lead Biomarker among Panel Beaters in Enugu Metropolis: Nigeria
The limited alternatives to blood lead biomarkers continue to affect the control of occupational lead exposures. This study assessed the relationship and accuracy of urine lead biomarker as an alternative to blood lead biomarker among roadside and organized panel beaters in Enugu metropolis, Nigeria...
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Veröffentlicht in: | Indian journal of occupational and environmental medicine 2023-10, Vol.27 (4), p.351-354 |
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description | The limited alternatives to blood lead biomarkers continue to affect the control of occupational lead exposures. This study assessed the relationship and accuracy of urine lead biomarker as an alternative to blood lead biomarker among roadside and organized panel beaters in Enugu metropolis, Nigeria.
This was a cross-sectional analytical study of 428 panel beaters in Enugu metropolis. Samples collected were analyzed using Atomic Absorption Spectrometer (AAS) at 283.3 nm wavelengths. Data were analyzed using correlation and receiver operating characteristics (ROC).
A linear positive relationship with high accuracy and sensitivity were found between blood and urine biomarkers.
Urine biomarker has a linear relationship with blood biomarker and showed a significant accuracy for the measurement of occupational lead exposure. Therefore, a urinary biomarker can serve as an alternative replacement to blood lead in occupational health practice. |
doi_str_mv | 10.4103/ijoem.ijoem_140_22 |
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This was a cross-sectional analytical study of 428 panel beaters in Enugu metropolis. Samples collected were analyzed using Atomic Absorption Spectrometer (AAS) at 283.3 nm wavelengths. Data were analyzed using correlation and receiver operating characteristics (ROC).
A linear positive relationship with high accuracy and sensitivity were found between blood and urine biomarkers.
Urine biomarker has a linear relationship with blood biomarker and showed a significant accuracy for the measurement of occupational lead exposure. Therefore, a urinary biomarker can serve as an alternative replacement to blood lead in occupational health practice.</description><identifier>ISSN: 0973-2284</identifier><identifier>EISSN: 1998-3670</identifier><identifier>DOI: 10.4103/ijoem.ijoem_140_22</identifier><identifier>PMID: 38390481</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Anabolic steroids ; Biological monitoring ; Biomarkers ; Blood ; Brief Communication ; Ethylenediaminetetraacetic acid ; Human exposure ; Lead content ; Urinalysis</subject><ispartof>Indian journal of occupational and environmental medicine, 2023-10, Vol.27 (4), p.351-354</ispartof><rights>Copyright: © 2023 Indian Journal of Occupational and Environmental Medicine.</rights><rights>COPYRIGHT 2023 Medknow Publications and Media Pvt. Ltd.</rights><rights>2023. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2023 Indian Journal of Occupational and Environmental Medicine 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c654t-3330af9d29265d57904af3025d80ad1a229d0d5893d679c741e99509d94785a73</citedby><cites>FETCH-LOGICAL-c654t-3330af9d29265d57904af3025d80ad1a229d0d5893d679c741e99509d94785a73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10880828/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10880828/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38390481$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kassy, Chukwukasi Wilson</creatorcontrib><title>Relationship and Accuracy of Urine Lead as an Alternative to Blood Lead Biomarker among Panel Beaters in Enugu Metropolis: Nigeria</title><title>Indian journal of occupational and environmental medicine</title><addtitle>Indian J Occup Environ Med</addtitle><description>The limited alternatives to blood lead biomarkers continue to affect the control of occupational lead exposures. This study assessed the relationship and accuracy of urine lead biomarker as an alternative to blood lead biomarker among roadside and organized panel beaters in Enugu metropolis, Nigeria.
This was a cross-sectional analytical study of 428 panel beaters in Enugu metropolis. Samples collected were analyzed using Atomic Absorption Spectrometer (AAS) at 283.3 nm wavelengths. Data were analyzed using correlation and receiver operating characteristics (ROC).
A linear positive relationship with high accuracy and sensitivity were found between blood and urine biomarkers.
Urine biomarker has a linear relationship with blood biomarker and showed a significant accuracy for the measurement of occupational lead exposure. Therefore, a urinary biomarker can serve as an alternative replacement to blood lead in occupational health practice.</description><subject>Anabolic steroids</subject><subject>Biological monitoring</subject><subject>Biomarkers</subject><subject>Blood</subject><subject>Brief Communication</subject><subject>Ethylenediaminetetraacetic acid</subject><subject>Human exposure</subject><subject>Lead content</subject><subject>Urinalysis</subject><issn>0973-2284</issn><issn>1998-3670</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNk11rFDEUhgdRbK3-AS8kIHg3az4mk8Qb2S31A9YPxF6HODkzm3U2WZOZQm_95cZurbOwLCWQQM7zvicnySmK5wTPKoLZa7cOsJndzJpUWFP6oDglSsmS1QI_LE6xEqykVFYnxZOU1hgzTmr1uDhhkilcSXJa_P4GvRlc8Gnltsh4i-ZNM0bTXKPQosvoPKAlGItMylE07weIPguuAA0BLfoQ7C6-cGFj4k-IyGyC79BX46FHCzBZkJDz6MKP3Yg-wRDDNvQuvUGfXQfRmafFo9b0CZ7drmfF5buL7-cfyuWX9x_P58uyqXk1lIwxbFplqaI1t1zkAkzLMOVWYmOJoVRZbLlUzNZCNaIioBTHyqpKSG4EOyve7ny3448N2Ab8EE2vt9Hlg1_rYJzej3i30l240gRLiSWV2eHlrUMMv0ZIg16HMV9HnzQjFa0xznd9jKKKcE4EE_g_1ZketPNtyDmbjUuNnkuiqlpQVh2lhFBcYlHxTJUHqA485DKCh9bl7T3X-_BT_9kBPg8LG9ccTHAvwTTDq4lgBaYfVin0483P3Hc-Ck4d6Q5sYkgpQnv30ATrv-2jd40zbZ8sejH9IneSf_3C_gDpdBM_</recordid><startdate>20231001</startdate><enddate>20231001</enddate><creator>Kassy, Chukwukasi Wilson</creator><general>Medknow Publications and Media Pvt. 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This study assessed the relationship and accuracy of urine lead biomarker as an alternative to blood lead biomarker among roadside and organized panel beaters in Enugu metropolis, Nigeria.
This was a cross-sectional analytical study of 428 panel beaters in Enugu metropolis. Samples collected were analyzed using Atomic Absorption Spectrometer (AAS) at 283.3 nm wavelengths. Data were analyzed using correlation and receiver operating characteristics (ROC).
A linear positive relationship with high accuracy and sensitivity were found between blood and urine biomarkers.
Urine biomarker has a linear relationship with blood biomarker and showed a significant accuracy for the measurement of occupational lead exposure. Therefore, a urinary biomarker can serve as an alternative replacement to blood lead in occupational health practice.</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>38390481</pmid><doi>10.4103/ijoem.ijoem_140_22</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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source | Medknow Open Access Medical Journals; PubMed Central Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central |
subjects | Anabolic steroids Biological monitoring Biomarkers Blood Brief Communication Ethylenediaminetetraacetic acid Human exposure Lead content Urinalysis |
title | Relationship and Accuracy of Urine Lead as an Alternative to Blood Lead Biomarker among Panel Beaters in Enugu Metropolis: Nigeria |
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