Revisiting Cytomegalovirus Serology in Allogeneic Hematopoietic Cell Transplant Recipients

Revisiting Cytomegalovirus Serology in Allogeneic Hematopoietic Cell Transplant Recipients

Allogeneic hematopoietic cell transplant recipients (allo-HCTRs) with positive cytomegalovirus (CMV) serology may have false-positive results due to blood product transfusion-associated passive immunity. This single-center cohort study included allo-HCTRs with negative baseline (at malignancy diagno...

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Veröffentlicht in:Clinical infectious diseases 2024-02, Vol.78 (2), p.423-429
Hauptverfasser: Portillo, Vera, Masouridi-Levrat, Stavroula, Royston, Léna, Yerly, Sabine, Schibler, Manuel, Mappoura, Maria, Morin, Sarah, Giannotti, Federica, Mamez, Anne-Claire, van Delden, Christian, Chalandon, Yves, Neofytos, Dionysios
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies, Viral - therapeutic use
Cohort Studies
Cytomegalovirus
Cytomegalovirus Infections
Hematopoietic Stem Cell Transplantation - adverse effects
Humans
Immunoglobulin G
Major
Retrospective Studies
Transplant Recipients
Transplantation, Homologous - adverse effects
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Zusammenfassung:Allogeneic hematopoietic cell transplant recipients (allo-HCTRs) with positive cytomegalovirus (CMV) serology may have false-positive results due to blood product transfusion-associated passive immunity. This single-center cohort study included allo-HCTRs with negative baseline (at malignancy diagnosis) CMV serology and indeterminate/low-positive (CMV IgG titer, ≥0.6-
ISSN:1058-4838
1537-6591
1537-6591
DOI:10.1093/cid/ciad550