SARM1 is responsible for calpain-dependent dendrite degeneration in mouse hippocampal neurons

Sterile alpha and toll/interleukin receptor motif-containing 1 (SARM1) is a critical regulator of axon degeneration that acts through hydrolysis of NAD+ following injury. Recent work has defined the mechanisms underlying SARM1’s catalytic activity and advanced our understanding of SARM1 function in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2024-02, Vol.300 (2), p.105630-105630, Article 105630
Hauptverfasser:	Miyamoto, Takashi, Kim, Chaeyoung, Chow, Johann, Dugas, Jason C., DeGroot, Jack, Bagdasarian, Alex L., Thottumkara, Arun P., Larhammar, Martin, Calvert, Meredith EK, Fox, Brian M., Lewcock, Joseph W., Kane, Lesley A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Armadillo Domain Proteins - genetics Armadillo Domain Proteins - metabolism axon Axons - metabolism calcium calpain Calpain - metabolism Cytoskeletal Proteins - metabolism dendrite Dendrites - metabolism Mice neurodegeneration Neurons - metabolism SARM1 Signal Transduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!