Development of a molecularly imprinted polymer-based electrochemical sensor for the selective detection of nerve agent VX metabolite ethyl methylphosphonic acid in human plasma and urine samples

This study focuses on the detection of ethyl methyl phosphonic acid (EMPA), a metabolite of the banned organophosphorus nerve agent VX. We developed an electrochemical sensor utilizing the molecularly imprinted polymer (MIP) based on 4-aminobenzoic acid (4-ABA) and tetraethyl orthosilicate for the s...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2024-03, Vol.416 (6), p.1505-1515
Hauptverfasser:	Sezigen, Sermet, Kaya, S. Irem, Bakirhan, Nurgul K., Ozkan, Sibel A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Biochemistry Blood plasma Characterization and Evaluation of Materials Chemical sensors Chemistry Chemistry and Materials Science Detection limits dielectric spectroscopy Electrochemical impedance spectroscopy Electrochemistry Food Science Glassy carbon glassy carbon electrode humans Imprinted polymers Laboratory Medicine Metabolites molecular imprinting Monitoring/Environmental Analysis Nerve agents Nerves para-Aminobenzoic acid Phosphonic acids phosphorous acid Plasma polymerization Polymers Research Paper Sensors sensors (equipment) Spectroscopy Target detection Tetraethoxysilane Tetraethyl orthosilicate Urine voltammetry
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