A Comparison of Chlorhexidine-Alcohol and Povidone-Iodine-Alcohol on the Incidence of Surgical Site Infection
Surgical site infection (SSI) persists as a global challenge, accounting for 20%-25% of all healthcare-associated infections. The SSI rate has been reported to range from 2.5% to 41.9%. Skin preparation with acceptable antiseptic preparations has a high recommendation from the Centers for Disease Co...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2024-01, Vol.16 (1), p.e51901-e51901 |
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| creator | Fakoya, Adegbolahan Afolabi, Adefemi Ayandipo, Omobolaji Makanjuola, Olufunmilola Adepoju, Olalekan Ajagbe, Oluwasanmi Afuwape, Oludolapo O |
| description | Surgical site infection (SSI) persists as a global challenge, accounting for 20%-25% of all healthcare-associated infections. The SSI rate has been reported to range from 2.5% to 41.9%. Skin preparation with acceptable antiseptic preparations has a high recommendation from the Centers for Disease Control as an SSI preventive measure.
The aim was to compare the efficacy of 10% povidone-iodine in 70% isopropyl alcohol with 2% chlorhexidine in 70% isopropyl alcohol in preventing SSI.
This prospective randomized study included patients who were followed up for 30 days looking for SSI. Swabs were taken from wounds that developed SSI. A culture of all swabs was done.
One hundred and fifty-three patients were recruited into the study. Overall, eight (5.23%) of the 153 patients developed SSI. The SSI rate in clean wounds was 2.6%, while the SSI rate in clean-contaminated wounds was 7.9%. No statistically significant difference was found (p=0.141) between the two groups. |
| doi_str_mv | 10.7759/cureus.51901 |
| format | Article |
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The aim was to compare the efficacy of 10% povidone-iodine in 70% isopropyl alcohol with 2% chlorhexidine in 70% isopropyl alcohol in preventing SSI.
This prospective randomized study included patients who were followed up for 30 days looking for SSI. Swabs were taken from wounds that developed SSI. A culture of all swabs was done.
One hundred and fifty-three patients were recruited into the study. Overall, eight (5.23%) of the 153 patients developed SSI. The SSI rate in clean wounds was 2.6%, while the SSI rate in clean-contaminated wounds was 7.9%. No statistically significant difference was found (p=0.141) between the two groups.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.51901</identifier><identifier>PMID: 38333453</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Alcohol ; Antibiotics ; Body mass index ; Emergency medical care ; Epidemiology/Public Health ; General Surgery ; Hypertension ; Infectious Disease ; Iodine ; Medical personnel ; Patients ; Skin ; Surgeons ; Surgical site infections</subject><ispartof>Curēus (Palo Alto, CA), 2024-01, Vol.16 (1), p.e51901-e51901</ispartof><rights>Copyright © 2024, Fakoya et al.</rights><rights>Copyright © 2024, Fakoya et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2024, Fakoya et al. 2024 Fakoya et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c300t-6a01193228e703cdabf633e3cc8287d9aa9b6a87bff5c17467f3b57c831d476b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10849996/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10849996/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38333453$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fakoya, Adegbolahan</creatorcontrib><creatorcontrib>Afolabi, Adefemi</creatorcontrib><creatorcontrib>Ayandipo, Omobolaji</creatorcontrib><creatorcontrib>Makanjuola, Olufunmilola</creatorcontrib><creatorcontrib>Adepoju, Olalekan</creatorcontrib><creatorcontrib>Ajagbe, Oluwasanmi</creatorcontrib><creatorcontrib>Afuwape, Oludolapo O</creatorcontrib><title>A Comparison of Chlorhexidine-Alcohol and Povidone-Iodine-Alcohol on the Incidence of Surgical Site Infection</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Surgical site infection (SSI) persists as a global challenge, accounting for 20%-25% of all healthcare-associated infections. The SSI rate has been reported to range from 2.5% to 41.9%. Skin preparation with acceptable antiseptic preparations has a high recommendation from the Centers for Disease Control as an SSI preventive measure.
The aim was to compare the efficacy of 10% povidone-iodine in 70% isopropyl alcohol with 2% chlorhexidine in 70% isopropyl alcohol in preventing SSI.
This prospective randomized study included patients who were followed up for 30 days looking for SSI. Swabs were taken from wounds that developed SSI. A culture of all swabs was done.
One hundred and fifty-three patients were recruited into the study. Overall, eight (5.23%) of the 153 patients developed SSI. The SSI rate in clean wounds was 2.6%, while the SSI rate in clean-contaminated wounds was 7.9%. No statistically significant difference was found (p=0.141) between the two groups.</description><subject>Alcohol</subject><subject>Antibiotics</subject><subject>Body mass index</subject><subject>Emergency medical care</subject><subject>Epidemiology/Public Health</subject><subject>General Surgery</subject><subject>Hypertension</subject><subject>Infectious Disease</subject><subject>Iodine</subject><subject>Medical personnel</subject><subject>Patients</subject><subject>Skin</subject><subject>Surgeons</subject><subject>Surgical site infections</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkc1LxDAQxYMoKurNsxS8eLCadNomOcmy-LGwoLB6Dmma2kibrEm76H9v1lVRTxnyfvOYmYfQMcEXlBb8Uo1ej-GiIByTLbSfkZKljLB8-1e9h45CeMEYE0wzTPEu2gMGAHkB-6ifJFPXL6U3wdnENcm07Zxv9ZupjdXppFOudV0ibZ08uJWpXfycuT9a7BtancysMrW2Sq9dFqN_Nkp2ycIMa6nRajDOHqKdRnZBH329B-jp5vpxepfO729n08k8VYDxkJYSE8Ihy5imGFQtq6YE0KAUyxituZS8KiWjVdMUitC8pA1UBVUMSJ3TsoIDdLXxXY5Vr2ul7eBlJ5be9NK_CyeN-KtY04pntxIEs5xzXkaHsy8H715HHQbRm6B010mr3RhExrMCQ7wujejpP_TFjd7G_SIV7wxZnCtS5xtKeReC183PNASLdZZik6X4zDLiJ783-IG_k4MPfRWb9g</recordid><startdate>20240108</startdate><enddate>20240108</enddate><creator>Fakoya, Adegbolahan</creator><creator>Afolabi, Adefemi</creator><creator>Ayandipo, Omobolaji</creator><creator>Makanjuola, Olufunmilola</creator><creator>Adepoju, Olalekan</creator><creator>Ajagbe, Oluwasanmi</creator><creator>Afuwape, Oludolapo O</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20240108</creationdate><title>A Comparison of Chlorhexidine-Alcohol and Povidone-Iodine-Alcohol on the Incidence of Surgical Site Infection</title><author>Fakoya, Adegbolahan ; Afolabi, Adefemi ; Ayandipo, Omobolaji ; Makanjuola, Olufunmilola ; Adepoju, Olalekan ; Ajagbe, Oluwasanmi ; Afuwape, Oludolapo O</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c300t-6a01193228e703cdabf633e3cc8287d9aa9b6a87bff5c17467f3b57c831d476b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Alcohol</topic><topic>Antibiotics</topic><topic>Body mass index</topic><topic>Emergency medical care</topic><topic>Epidemiology/Public Health</topic><topic>General Surgery</topic><topic>Hypertension</topic><topic>Infectious Disease</topic><topic>Iodine</topic><topic>Medical personnel</topic><topic>Patients</topic><topic>Skin</topic><topic>Surgeons</topic><topic>Surgical site infections</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fakoya, Adegbolahan</creatorcontrib><creatorcontrib>Afolabi, Adefemi</creatorcontrib><creatorcontrib>Ayandipo, Omobolaji</creatorcontrib><creatorcontrib>Makanjuola, Olufunmilola</creatorcontrib><creatorcontrib>Adepoju, Olalekan</creatorcontrib><creatorcontrib>Ajagbe, Oluwasanmi</creatorcontrib><creatorcontrib>Afuwape, Oludolapo O</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fakoya, Adegbolahan</au><au>Afolabi, Adefemi</au><au>Ayandipo, Omobolaji</au><au>Makanjuola, Olufunmilola</au><au>Adepoju, Olalekan</au><au>Ajagbe, Oluwasanmi</au><au>Afuwape, Oludolapo O</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Comparison of Chlorhexidine-Alcohol and Povidone-Iodine-Alcohol on the Incidence of Surgical Site Infection</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2024-01-08</date><risdate>2024</risdate><volume>16</volume><issue>1</issue><spage>e51901</spage><epage>e51901</epage><pages>e51901-e51901</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Surgical site infection (SSI) persists as a global challenge, accounting for 20%-25% of all healthcare-associated infections. The SSI rate has been reported to range from 2.5% to 41.9%. Skin preparation with acceptable antiseptic preparations has a high recommendation from the Centers for Disease Control as an SSI preventive measure.
The aim was to compare the efficacy of 10% povidone-iodine in 70% isopropyl alcohol with 2% chlorhexidine in 70% isopropyl alcohol in preventing SSI.
This prospective randomized study included patients who were followed up for 30 days looking for SSI. Swabs were taken from wounds that developed SSI. A culture of all swabs was done.
One hundred and fifty-three patients were recruited into the study. Overall, eight (5.23%) of the 153 patients developed SSI. The SSI rate in clean wounds was 2.6%, while the SSI rate in clean-contaminated wounds was 7.9%. No statistically significant difference was found (p=0.141) between the two groups.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>38333453</pmid><doi>10.7759/cureus.51901</doi><oa>free_for_read</oa></addata></record> |
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| source | PubMed Central; PubMed Central Open Access |
| subjects | Alcohol Antibiotics Body mass index Emergency medical care Epidemiology/Public Health General Surgery Hypertension Infectious Disease Iodine Medical personnel Patients Skin Surgeons Surgical site infections |
| title | A Comparison of Chlorhexidine-Alcohol and Povidone-Iodine-Alcohol on the Incidence of Surgical Site Infection |
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