biphasic mRNA expression pattern of bovine interleukin-8 in Pasteurella haemolytica lipopolysaccharide-stimulated alveolar macrophages is primarily due to tumor necrosis factor alpha

Pasteurella haemolytica serotype 1 is the bacterial agent responsible for the pathophysiological events associated with bovine pneumonic pasteurellosis. Our previous studies support a role for the lipopolysaccharide (LPS) from P. haemolytica in the induction of proinflammatory cytokines. One of the...

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Veröffentlicht in:	Infection and immunity 1998-09, Vol.66 (9), p.4087-4092
Hauptverfasser:	Lafleur, R.L, Abrahamsen, M.S, Maheswaran, S.K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - metabolism Bacteriology Biological and medical sciences Cattle Cloning, Molecular DNA, Complementary Fundamental and applied biological sciences. Psychology gene expression Gene Expression Regulation - drug effects Host Response and Inflammation Humans Interleukin-8 - genetics Kinetics Lipopolysaccharides - immunology Lipopolysaccharides - pharmacology Macrophages, Alveolar - drug effects Macrophages, Alveolar - immunology Mannheimia haemolytica - immunology messenger RNA Microbiology Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Recombinant Proteins - pharmacology RNA, Messenger Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - immunology Tumor Necrosis Factor-alpha - metabolism Tumor Necrosis Factor-alpha - pharmacology
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