Amiodarone-Induced Leukocytoclastic Vasculitis in a Decompensated Heart Failure Patient: A Case Report
Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis characterized by inflammation and damage to the walls of small blood vessels. It typically presents with palpable purpura and can be associated with various systemic conditions. Although its etiology is diverse, LCV has been associated w...
Gespeichert in:
| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2024-01, Vol.16 (1), p.e51817 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 1 |
| container_start_page | e51817 |
| container_title | Curēus (Palo Alto, CA) |
| container_volume | 16 |
| creator | Asfeen, Ummul Raj, Rohan Ezeafulukwe, Chinedu J Hassan, Omar A Francis, Deepa Treesa Dhillon, Sukhmeet S Khan, Aadil |
| description | Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis characterized by inflammation and damage to the walls of small blood vessels. It typically presents with palpable purpura and can be associated with various systemic conditions. Although its etiology is diverse, LCV has been associated with systemic diseases, infections, medications, and autoimmune disorders. Here, we present a case of LCV in a patient with decompensated heart failure. A 58-year-old man presented with progressively deteriorating swelling in both his lower limbs and scrotum, a persistent dry cough associated with minor ulcerative lesions on his shins, and a patchy rash with pustules and flat reddish spots. He was hospitalized three days prior due to atrial fibrillation and rapid ventricular rate, for which he was commenced on amiodarone. This rash persisted for three days, yet he denied experiencing any discomfort or itchiness along with it. Based on his clinical picture, laboratory evaluations, and imaging findings, he was diagnosed with LCV induced by amiodarone. |
| doi_str_mv | 10.7759/cureus.51817 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10847063</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2933442810</sourcerecordid><originalsourceid>FETCH-LOGICAL-c267t-cdfc794922729dc5ad383be5568dbf04506908f7225d22777a37860ec4efad3</originalsourceid><addsrcrecordid>eNpVkU1LAzEQhoMotlRvniXg1dUk-5GsFyn1EwqKiteQJrOaut3UJCv4741WSz3NwDy888CL0AElJ5yX9anuPfThpKSC8i00ZLQSmaCi2N7YB2g_hDkhhBLOCCe7aJCLnPGaVEPUjBfWGeVdB9ltZ3oNBk-hf3P6MzrdqhCtxs8q6L610QZsO6zwBWi3WEIXVEz4DSgf8ZWybZLB9ypa6OIZHuOJCoAfYOl83EM7jWoD7P_OEXq8unya3GTTu-vbyXiaaVbxmGnTaF4XNWOc1UaXyiTTGZRlJcysIUVJqpqIhjNWmsRwrnIuKgK6gCaxI3S-Sl32swUYnTy8auXS24Xyn9IpK_9fOvsqX9yHpEQUnFR5Sjj6TfDuvYcQ5dz1vkvKktV5XhRMUJKo4xWlvQvBQ7N-QYn87kWuepE_vST8cFNrDf-1kH8Bd6iLXw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2933442810</pqid></control><display><type>article</type><title>Amiodarone-Induced Leukocytoclastic Vasculitis in a Decompensated Heart Failure Patient: A Case Report</title><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Asfeen, Ummul ; Raj, Rohan ; Ezeafulukwe, Chinedu J ; Hassan, Omar A ; Francis, Deepa Treesa ; Dhillon, Sukhmeet S ; Khan, Aadil</creator><creatorcontrib>Asfeen, Ummul ; Raj, Rohan ; Ezeafulukwe, Chinedu J ; Hassan, Omar A ; Francis, Deepa Treesa ; Dhillon, Sukhmeet S ; Khan, Aadil</creatorcontrib><description>Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis characterized by inflammation and damage to the walls of small blood vessels. It typically presents with palpable purpura and can be associated with various systemic conditions. Although its etiology is diverse, LCV has been associated with systemic diseases, infections, medications, and autoimmune disorders. Here, we present a case of LCV in a patient with decompensated heart failure. A 58-year-old man presented with progressively deteriorating swelling in both his lower limbs and scrotum, a persistent dry cough associated with minor ulcerative lesions on his shins, and a patchy rash with pustules and flat reddish spots. He was hospitalized three days prior due to atrial fibrillation and rapid ventricular rate, for which he was commenced on amiodarone. This rash persisted for three days, yet he denied experiencing any discomfort or itchiness along with it. Based on his clinical picture, laboratory evaluations, and imaging findings, he was diagnosed with LCV induced by amiodarone.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.51817</identifier><identifier>PMID: 38327906</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Allergy/Immunology ; Antiarrhythmics ; Blood pressure ; Blood vessels ; Cardiac arrhythmia ; Cardiology ; Cardiovascular disease ; Case reports ; Dyspnea ; Edema ; Ejection fraction ; Electrocardiography ; Heart failure ; Heart transplants ; Hypertension ; Immunotherapy ; Infections ; Influenza ; Internal Medicine ; Ischemia ; Kinases ; Lupus ; Patients ; Urinalysis ; Vaccines</subject><ispartof>Curēus (Palo Alto, CA), 2024-01, Vol.16 (1), p.e51817</ispartof><rights>Copyright © 2024, Asfeen et al.</rights><rights>Copyright © 2024, Asfeen et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2024, Asfeen et al. 2024 Asfeen et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c267t-cdfc794922729dc5ad383be5568dbf04506908f7225d22777a37860ec4efad3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10847063/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10847063/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38327906$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Asfeen, Ummul</creatorcontrib><creatorcontrib>Raj, Rohan</creatorcontrib><creatorcontrib>Ezeafulukwe, Chinedu J</creatorcontrib><creatorcontrib>Hassan, Omar A</creatorcontrib><creatorcontrib>Francis, Deepa Treesa</creatorcontrib><creatorcontrib>Dhillon, Sukhmeet S</creatorcontrib><creatorcontrib>Khan, Aadil</creatorcontrib><title>Amiodarone-Induced Leukocytoclastic Vasculitis in a Decompensated Heart Failure Patient: A Case Report</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis characterized by inflammation and damage to the walls of small blood vessels. It typically presents with palpable purpura and can be associated with various systemic conditions. Although its etiology is diverse, LCV has been associated with systemic diseases, infections, medications, and autoimmune disorders. Here, we present a case of LCV in a patient with decompensated heart failure. A 58-year-old man presented with progressively deteriorating swelling in both his lower limbs and scrotum, a persistent dry cough associated with minor ulcerative lesions on his shins, and a patchy rash with pustules and flat reddish spots. He was hospitalized three days prior due to atrial fibrillation and rapid ventricular rate, for which he was commenced on amiodarone. This rash persisted for three days, yet he denied experiencing any discomfort or itchiness along with it. Based on his clinical picture, laboratory evaluations, and imaging findings, he was diagnosed with LCV induced by amiodarone.</description><subject>Allergy/Immunology</subject><subject>Antiarrhythmics</subject><subject>Blood pressure</subject><subject>Blood vessels</subject><subject>Cardiac arrhythmia</subject><subject>Cardiology</subject><subject>Cardiovascular disease</subject><subject>Case reports</subject><subject>Dyspnea</subject><subject>Edema</subject><subject>Ejection fraction</subject><subject>Electrocardiography</subject><subject>Heart failure</subject><subject>Heart transplants</subject><subject>Hypertension</subject><subject>Immunotherapy</subject><subject>Infections</subject><subject>Influenza</subject><subject>Internal Medicine</subject><subject>Ischemia</subject><subject>Kinases</subject><subject>Lupus</subject><subject>Patients</subject><subject>Urinalysis</subject><subject>Vaccines</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpVkU1LAzEQhoMotlRvniXg1dUk-5GsFyn1EwqKiteQJrOaut3UJCv4741WSz3NwDy888CL0AElJ5yX9anuPfThpKSC8i00ZLQSmaCi2N7YB2g_hDkhhBLOCCe7aJCLnPGaVEPUjBfWGeVdB9ltZ3oNBk-hf3P6MzrdqhCtxs8q6L610QZsO6zwBWi3WEIXVEz4DSgf8ZWybZLB9ypa6OIZHuOJCoAfYOl83EM7jWoD7P_OEXq8unya3GTTu-vbyXiaaVbxmGnTaF4XNWOc1UaXyiTTGZRlJcysIUVJqpqIhjNWmsRwrnIuKgK6gCaxI3S-Sl32swUYnTy8auXS24Xyn9IpK_9fOvsqX9yHpEQUnFR5Sjj6TfDuvYcQ5dz1vkvKktV5XhRMUJKo4xWlvQvBQ7N-QYn87kWuepE_vST8cFNrDf-1kH8Bd6iLXw</recordid><startdate>20240107</startdate><enddate>20240107</enddate><creator>Asfeen, Ummul</creator><creator>Raj, Rohan</creator><creator>Ezeafulukwe, Chinedu J</creator><creator>Hassan, Omar A</creator><creator>Francis, Deepa Treesa</creator><creator>Dhillon, Sukhmeet S</creator><creator>Khan, Aadil</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>5PM</scope></search><sort><creationdate>20240107</creationdate><title>Amiodarone-Induced Leukocytoclastic Vasculitis in a Decompensated Heart Failure Patient: A Case Report</title><author>Asfeen, Ummul ; Raj, Rohan ; Ezeafulukwe, Chinedu J ; Hassan, Omar A ; Francis, Deepa Treesa ; Dhillon, Sukhmeet S ; Khan, Aadil</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c267t-cdfc794922729dc5ad383be5568dbf04506908f7225d22777a37860ec4efad3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Allergy/Immunology</topic><topic>Antiarrhythmics</topic><topic>Blood pressure</topic><topic>Blood vessels</topic><topic>Cardiac arrhythmia</topic><topic>Cardiology</topic><topic>Cardiovascular disease</topic><topic>Case reports</topic><topic>Dyspnea</topic><topic>Edema</topic><topic>Ejection fraction</topic><topic>Electrocardiography</topic><topic>Heart failure</topic><topic>Heart transplants</topic><topic>Hypertension</topic><topic>Immunotherapy</topic><topic>Infections</topic><topic>Influenza</topic><topic>Internal Medicine</topic><topic>Ischemia</topic><topic>Kinases</topic><topic>Lupus</topic><topic>Patients</topic><topic>Urinalysis</topic><topic>Vaccines</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Asfeen, Ummul</creatorcontrib><creatorcontrib>Raj, Rohan</creatorcontrib><creatorcontrib>Ezeafulukwe, Chinedu J</creatorcontrib><creatorcontrib>Hassan, Omar A</creatorcontrib><creatorcontrib>Francis, Deepa Treesa</creatorcontrib><creatorcontrib>Dhillon, Sukhmeet S</creatorcontrib><creatorcontrib>Khan, Aadil</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Asfeen, Ummul</au><au>Raj, Rohan</au><au>Ezeafulukwe, Chinedu J</au><au>Hassan, Omar A</au><au>Francis, Deepa Treesa</au><au>Dhillon, Sukhmeet S</au><au>Khan, Aadil</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Amiodarone-Induced Leukocytoclastic Vasculitis in a Decompensated Heart Failure Patient: A Case Report</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2024-01-07</date><risdate>2024</risdate><volume>16</volume><issue>1</issue><spage>e51817</spage><pages>e51817-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis characterized by inflammation and damage to the walls of small blood vessels. It typically presents with palpable purpura and can be associated with various systemic conditions. Although its etiology is diverse, LCV has been associated with systemic diseases, infections, medications, and autoimmune disorders. Here, we present a case of LCV in a patient with decompensated heart failure. A 58-year-old man presented with progressively deteriorating swelling in both his lower limbs and scrotum, a persistent dry cough associated with minor ulcerative lesions on his shins, and a patchy rash with pustules and flat reddish spots. He was hospitalized three days prior due to atrial fibrillation and rapid ventricular rate, for which he was commenced on amiodarone. This rash persisted for three days, yet he denied experiencing any discomfort or itchiness along with it. Based on his clinical picture, laboratory evaluations, and imaging findings, he was diagnosed with LCV induced by amiodarone.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>38327906</pmid><doi>10.7759/cureus.51817</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2168-8184 |
| ispartof | Curēus (Palo Alto, CA), 2024-01, Vol.16 (1), p.e51817 |
| issn | 2168-8184 2168-8184 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10847063 |
| source | PubMed Central Open Access; PubMed Central |
| subjects | Allergy/Immunology Antiarrhythmics Blood pressure Blood vessels Cardiac arrhythmia Cardiology Cardiovascular disease Case reports Dyspnea Edema Ejection fraction Electrocardiography Heart failure Heart transplants Hypertension Immunotherapy Infections Influenza Internal Medicine Ischemia Kinases Lupus Patients Urinalysis Vaccines |
| title | Amiodarone-Induced Leukocytoclastic Vasculitis in a Decompensated Heart Failure Patient: A Case Report |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T06%3A31%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Amiodarone-Induced%20Leukocytoclastic%20Vasculitis%20in%20a%20Decompensated%20Heart%20Failure%20Patient:%20A%20Case%20Report&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Asfeen,%20Ummul&rft.date=2024-01-07&rft.volume=16&rft.issue=1&rft.spage=e51817&rft.pages=e51817-&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.51817&rft_dat=%3Cproquest_pubme%3E2933442810%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2933442810&rft_id=info:pmid/38327906&rfr_iscdi=true |