Methylation of elongation factor 1A by yeast Efm4 or human eEF1A-KMT2 involves a beta-hairpin recognition motif and crosstalks with phosphorylation

Translation elongation factor 1A (eEF1A) is an essential and highly conserved protein required for protein synthesis in eukaryotes. In both Saccharomyces cerevisiae and human, five different methyltransferases methylate specific residues on eEF1A, making eEF1A the eukaryotic protein targeted by the...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 2024-02, Vol.300 (2), p.105639-105639, Article 105639
Hauptverfasser:	Hamey, Joshua J., Nguyen, Amy, Haddad, Mahdi, Vázquez-Campos, Xabier, Pfeiffer, Paige G., Wilkins, Marc R.
Format:	Artikel
Sprache:	eng
Schlagworte:	AlphaFold crosslinking mass spectrometry protein cross-linking protein methylation protein methyltransferase translation elongation factor
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!