Amino acid intake strategies define pluripotent cell states

Mammalian preimplantation development is associated with marked metabolic robustness, and embryos can develop under a wide variety of nutrient conditions, including even the complete absence of soluble amino acids. Here we show that mouse embryonic stem cells (ESCs) capture the unique metabolic stat...

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Veröffentlicht in:	Nature metabolism 2024-01, Vol.6 (1), p.127-140
Hauptverfasser:	Todorova, Pavlina K., Jackson, Benjamin T., Garg, Vidur, Paras, Katrina I., Brunner, Julia S., Bridgeman, Anna E., Chen, Yanyang, Baksh, Sanjeethan C., Yan, Jielin, Hadjantonakis, Anna-Katerina, Finley, Lydia W. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136/2086 631/443/319 631/532/2064 Amino Acids - metabolism Animals Biomedical and Life Sciences Blastocyst - metabolism Embryonic Stem Cells - metabolism Life Sciences Mammals - metabolism Mice Mouse Embryonic Stem Cells - metabolism Proteins - metabolism
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