CCR8 Signaling Regulates IL-25- and IL-33-Responsive Skin Group 2 Innate Lymphoid Cell Migration and Function

Group 2 innate lymphoid cells (ILC2s) are sentinels of barrier immunity, and their activation by the epithelial alarmins IL-25 and IL-33 is a defining trait. Here we identified a role for the chemokine receptor CCR8 in modulating skin ILC2 abundance and activation. CCR8 signaling facilitated IL-25 i...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of immunology (1950) 2023-12, Vol.211 (12), p.1751-1755
Hauptverfasser:	Sun, Zhengwang, Han, Sen, Zhu, Xueping, Islam, Sabina A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!