Membrane-derived particles shed by PSMA-positive cells function as pro-angiogenic stimuli in tumors

Cell membrane-derived particles (Mp) are rounded membrane-enclosed particles that are shed from tumor cells. Mp are formed from tumor membranes and are capable of tumor targeting and immunotherapeutic agents because they share membrane homology with parental cells; thus, they are under consideration...

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Veröffentlicht in:	Journal of controlled release 2023-12, Vol.364, p.312-325
Hauptverfasser:	Machado, Camila M.L., Skubal, Magdalena, Haedicke, Katja, Silva, Fabio P., Stater, Evan P., Silva, Thais L.A. de O., Costa, Erico T., Masotti, Cibele, Otake, Andreia H., Andrade, Luciana N.S., Junqueira, Mara de S., Hsu, Hsiao-Ting, Das, Sudeep, Larney, Benedict Mc, Pratt, Edwin C., Romin, Yevgeniy, Fan, Ning, Manova-Todorova, Katia, Pomper, Martin, Grimm, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Angiogenin Cell Membrane - metabolism Humans Male Microenvironment Prostatic Neoplasms - pathology PSMA-cell-membrane derived particles Tumor Microenvironment Vascular Endothelial Growth Factor A VEGF-A
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