Exploring reciprocal causation: bidirectional mendelian randomization study of gut microbiota composition and thyroid cancer

Background While an association between gut microbiota composition and thyroid cancer (TC) has been observed, the directionality and causality of this relationship remain unclear. Methods We conducted a bidirectional two-sample Mendelian randomization (MR) analysis to investigate the causal effect b...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2024-02, Vol.150 (2), p.75, Article 75
Hauptverfasser:	Zhou, Jiating, Zhang, Xuan, Xie, Zilan, Li, Zhi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Research Ethnicity Gastrointestinal Microbiome - genetics Genome-Wide Association Study Hematology Humans Internal Medicine Intestinal microflora Medicine Medicine & Public Health Mendelian Randomization Analysis Microbiota Oncology Pleiotropy Risk Factors Sensitivity analysis Single-nucleotide polymorphism Statistical analysis Thyroid cancer Thyroid Neoplasms - genetics
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