NCOA4 requires a [3Fe-4S] to sense and maintain the iron homeostasis

NCOA4 is a selective cargo receptor for ferritinophagy, the autophagic turnover of ferritin (FTH), a process critical for regulating intracellular iron bioavailability. However, how ferritinophagy flux is controlled through NCOA4 in iron-dependent processes needs to be better understood. Here, we sh...

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Veröffentlicht in:	The Journal of biological chemistry 2024-02, Vol.300 (2), p.105612-105612, Article 105612
Hauptverfasser:	Zhao, Hongting, Lu, Yao, Zhang, Jinghua, Sun, Zichen, Cheng, Chen, Liu, Yutong, Wu, Lin, Zhang, Meng, He, Weijiang, Hao, Shuangying, Li, Kuanyu
Format:	Artikel
Sprache:	eng
Schlagworte:	autophagy ferritin iron metabolism iron-sulfur protein NCOA4 protein degradation
Online-Zugang:	Volltext
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