The noradrenergic system in Alzheimer and multi-infarct dementias

The number of melanin containing nerve cells of the locus coeruleus and vagus nucleus is reduced in Alzheimer's disease by 60% with decrease of 22% in the protein synthetic capability of remaining cells. These changes are matched by reductions in brain noradrenaline in eight regions, averaging...

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1982-02, Vol.45 (2), p.113-119
Hauptverfasser:	Mann, D M, Yates, P O, Hawkes, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alzheimer Disease - metabolism Alzheimer Disease - pathology Brain - metabolism Cerebral Infarction - metabolism Cerebral Infarction - pathology Dementia - metabolism Dementia - pathology Female Humans Locus Coeruleus - pathology Male Melanins - metabolism Neurofibrils - ultrastructure Neurons - ultrastructure Norepinephrine - metabolism Vagus Nerve - pathology
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