Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy

The only FDA-approved oral immunotherapy for a food allergy provides protection against accidental exposure to peanuts. However, this therapy often causes discomfort or side effects and requires long-term commitment. Better preventive and therapeutic solutions are urgently needed. We develop a toler...

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Veröffentlicht in:Cell reports. Medicine 2024-01, Vol.5 (1), p.101346, Article 101346
Hauptverfasser: Cao, Shijie, Maulloo, Chitavi D, Raczy, Michal M, Sabados, Matthew, Slezak, Anna J, Nguyen, Mindy, Solanki, Ani, Wallace, Rachel P, Shim, Ha-Na, Wilson, D Scott, Hubbell, Jeffrey A
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Sprache:eng
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