Serum methylmalonic acid concentrations at breast cancer diagnosis significantly correlate with clinical frailty

Methylmalonic acid (MMA), a by-product of propionate metabolism, is known to increase with age. This study investigates the potential of serum MMA concentrations as a biomarker for age-related clinical frailty in older patients with breast cancer. One hundred nineteen patients ≥ 70 years old with ea...

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Veröffentlicht in:	GeroScience 2024-04, Vol.46 (2), p.1489-1498
Hauptverfasser:	Wu, Qi, Hatse, Sigrid, Kenis, Cindy, Fernández-García, Juan, Altea-Manzano, Patricia, Billen, Jaak, Planque, Mélanie, Vandekeere, Anke, Lambrechts, Yentl, Richard, François, Punie, Kevin, Neven, Patrick, Smeets, Ann, Nevelsteen, Ines, Floris, Giuseppe, Desmedt, Christine, Gomes, Ana P., Fendt, Sarah-Maria, Wildiers, Hans
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of Daily Living Age Aged Biomedical and Life Sciences Body mass index Breast cancer Breast Neoplasms - diagnosis Cell Biology Comorbidity Diagnosis Epidermal growth factor receptors Female Frailty Frailty - complications Frailty - diagnosis Geriatrics Geriatrics/Gerontology Glomerular filtration rate Humans Life Sciences Liquid chromatography Mass spectroscopy Medical diagnosis Methylmalonic Acid Molecular Medicine Original Original Article
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