Oxygen gradient ektacytometry-derived biomarkers are associated with acute complications in sickle cell disease

We investigated the potential of the point of sickling (PoS; the pO2 tension at which red cells start to sickle), determined by oxygen gradient ektacytometry to serve as a biomarker associated with the incidence of acute sickle cell disease-related complications in 177 children and 50 adults. In the...

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Veröffentlicht in:	Blood advances 2024-01, Vol.8 (2), p.276-286
Hauptverfasser:	Rab, Minke A E, Kanne, Celeste K, Boisson, Camille, Bos, Jennifer, van Oirschot, Brigitte A, Houwing, Maite E, Renoux, Céline, Bartels, Marije, Rijneveld, Anita W, Nur, Erfan, Cnossen, Marjon H, Joly, Philippe, Nader, Elie, Fort, Romain, Connes, Philippe, van Wijk, Richard, Sheehan, Vivien A, van Beers, Eduard J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anemia, Sickle Cell Biomarkers - metabolism Child Erythrocytes - metabolism Erythrocytes, Abnormal - metabolism Humans Oxygen - metabolism Red Cells, Iron, and Erythropoiesis
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