Efficacy of a single dose of an otic ivermectin preparation or selamectin for the treatment of Otodectes cynotis infestation in naturally infected cats
Otodectes cynotis infestation is common in kittens housed in crowded environments like animal shelters. It is unknown how rapidly O cynotis is killed within the first 72 h of treatment with currently available products. Kittens ≥4 weeks of age with live O cynotis in both ears (AU) were administered...
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| Veröffentlicht in: | Journal of feline medicine and surgery 2011-08, Vol.13 (8), p.622-624 |
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| container_title | Journal of feline medicine and surgery |
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| creator | Nunn-Brooks, Lindsey Michael, Robin Ravitz, Lea B. Kordick, Dorsey Lappin, Michael R. |
| description | Otodectes cynotis infestation is common in kittens housed in crowded environments like animal shelters. It is unknown how rapidly
O cynotis is killed within the first 72
h of treatment with currently available products. Kittens ≥4 weeks of age with live
O cynotis in both ears (AU) were administered 0.5
ml of 0.01% ivermectin otic suspension (Acarexx; Idexx Pharmaceuticals) once, AU or selamectin (Revolution; Pfizer Animal Health) once, on the skin following the manufacturer’s instructions. Repeat microscopic examination was performed on individual ears based on a randomization schedule during the 72
h after treatment. There was no evidence of toxicity with either drug and administration of 0.01% ivermectin significantly reduced the time to live mite-free status compared to selamectin. Both drugs have an effect against
O cynotis as early as 10–12
h after administration with an increasing effect over time. |
| doi_str_mv | 10.1016/j.jfms.2011.03.003 |
| format | Article |
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O cynotis is killed within the first 72
h of treatment with currently available products. Kittens ≥4 weeks of age with live
O cynotis in both ears (AU) were administered 0.5
ml of 0.01% ivermectin otic suspension (Acarexx; Idexx Pharmaceuticals) once, AU or selamectin (Revolution; Pfizer Animal Health) once, on the skin following the manufacturer’s instructions. Repeat microscopic examination was performed on individual ears based on a randomization schedule during the 72
h after treatment. There was no evidence of toxicity with either drug and administration of 0.01% ivermectin significantly reduced the time to live mite-free status compared to selamectin. Both drugs have an effect against
O cynotis as early as 10–12
h after administration with an increasing effect over time.</description><identifier>ISSN: 1098-612X</identifier><identifier>ISSN: 1532-2750</identifier><identifier>EISSN: 1532-2750</identifier><identifier>DOI: 10.1016/j.jfms.2011.03.003</identifier><identifier>PMID: 21536472</identifier><language>eng</language><publisher>London, England: Elsevier Ltd</publisher><subject>Animals ; Antiparasitic Agents - administration & dosage ; Cat Diseases - drug therapy ; Cat Diseases - parasitology ; Cats ; Ear - parasitology ; Ivermectin - administration & dosage ; Ivermectin - analogs & derivatives ; Mite Infestations - drug therapy ; Mite Infestations - veterinary ; Short Communication ; Survival Analysis ; Treatment Outcome</subject><ispartof>Journal of feline medicine and surgery, 2011-08, Vol.13 (8), p.622-624</ispartof><rights>2011</rights><rights>2011 International Society of Feline Medicine and American Association of Feline Practitioners</rights><rights>Copyright © 2011. Published by Elsevier Ltd.</rights><rights>2011 International Society of Feline Medicine and American Association of Feline Practitioners 2011 International Society of Feline Medicine and American Association of Feline Practitioners</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c495t-7a06db62aa7bbf0b28f939420a44866c2af690d06c4a3287a49f3c004e8417263</citedby><cites>FETCH-LOGICAL-c495t-7a06db62aa7bbf0b28f939420a44866c2af690d06c4a3287a49f3c004e8417263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10822411/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10822411/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,21945,27830,27901,27902,44921,45309,53766,53768</link.rule.ids><linktorsrc>$$Uhttps://journals.sagepub.com/doi/full/10.1016/j.jfms.2011.03.003?utm_source=summon&utm_medium=discovery-provider$$EView_record_in_SAGE_Publications$$FView_record_in_$$GSAGE_Publications</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21536472$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nunn-Brooks, Lindsey</creatorcontrib><creatorcontrib>Michael, Robin</creatorcontrib><creatorcontrib>Ravitz, Lea B.</creatorcontrib><creatorcontrib>Kordick, Dorsey</creatorcontrib><creatorcontrib>Lappin, Michael R.</creatorcontrib><title>Efficacy of a single dose of an otic ivermectin preparation or selamectin for the treatment of Otodectes cynotis infestation in naturally infected cats</title><title>Journal of feline medicine and surgery</title><addtitle>J Feline Med Surg</addtitle><description>Otodectes cynotis infestation is common in kittens housed in crowded environments like animal shelters. It is unknown how rapidly
O cynotis is killed within the first 72
h of treatment with currently available products. Kittens ≥4 weeks of age with live
O cynotis in both ears (AU) were administered 0.5
ml of 0.01% ivermectin otic suspension (Acarexx; Idexx Pharmaceuticals) once, AU or selamectin (Revolution; Pfizer Animal Health) once, on the skin following the manufacturer’s instructions. Repeat microscopic examination was performed on individual ears based on a randomization schedule during the 72
h after treatment. There was no evidence of toxicity with either drug and administration of 0.01% ivermectin significantly reduced the time to live mite-free status compared to selamectin. Both drugs have an effect against
O cynotis as early as 10–12
h after administration with an increasing effect over time.</description><subject>Animals</subject><subject>Antiparasitic Agents - administration & dosage</subject><subject>Cat Diseases - drug therapy</subject><subject>Cat Diseases - parasitology</subject><subject>Cats</subject><subject>Ear - parasitology</subject><subject>Ivermectin - administration & dosage</subject><subject>Ivermectin - analogs & derivatives</subject><subject>Mite Infestations - drug therapy</subject><subject>Mite Infestations - veterinary</subject><subject>Short Communication</subject><subject>Survival Analysis</subject><subject>Treatment Outcome</subject><issn>1098-612X</issn><issn>1532-2750</issn><issn>1532-2750</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UctuEzEUHSEQfcAPsEDesUp67XE8MxISQlWhSJW6AYmddeO5Tj2asYPtiZQv4XdxmlDBpis_zuM-TlW947DkwNXVsBzslJYCOF9CvQSoX1TnfFWLhWhW8LLcoWsXioufZ9VFSgMAdHUnXldnorCUbMR59fvGWmfQ7FmwDFlyfjMS60Oixw_PQnaGuR3FiUx2nm0jbTFidqFgkSUa8YTY8swPxHIkzBP5fHC4z6EvMCVm9r54Jea8pZSPBkXlMc8Rx3H_CBRmzwzm9KZ6ZXFM9PZ0XlY_vtx8v75d3N1__Xb9-W5hZLfKiwZB9WslEJv12sJatLaMKAWglK1SRqBVHfSgjMRatA3KztYGQFIreSNUfVl9Ovpu5_VEvSltl270NroJ414HdPp_xLsHvQk7zaEVQnJeHD6cHGL4NZfR9OSSoXFET2FOum2h4Uq2TWGKI9PEkFIk-1SGgz4kqgd9SFQfEtVQ65JoEb3_t8Enyd8IC-HqSEi4IT2EOfqysOctPx4VVBa7cxR1Mo68od7FkoDug3tO_gfQ7sVe</recordid><startdate>20110801</startdate><enddate>20110801</enddate><creator>Nunn-Brooks, Lindsey</creator><creator>Michael, Robin</creator><creator>Ravitz, Lea B.</creator><creator>Kordick, Dorsey</creator><creator>Lappin, Michael R.</creator><general>Elsevier Ltd</general><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20110801</creationdate><title>Efficacy of a single dose of an otic ivermectin preparation or selamectin for the treatment of Otodectes cynotis infestation in naturally infected cats</title><author>Nunn-Brooks, Lindsey ; Michael, Robin ; Ravitz, Lea B. ; Kordick, Dorsey ; Lappin, Michael R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c495t-7a06db62aa7bbf0b28f939420a44866c2af690d06c4a3287a49f3c004e8417263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Animals</topic><topic>Antiparasitic Agents - administration & dosage</topic><topic>Cat Diseases - drug therapy</topic><topic>Cat Diseases - parasitology</topic><topic>Cats</topic><topic>Ear - parasitology</topic><topic>Ivermectin - administration & dosage</topic><topic>Ivermectin - analogs & derivatives</topic><topic>Mite Infestations - drug therapy</topic><topic>Mite Infestations - veterinary</topic><topic>Short Communication</topic><topic>Survival Analysis</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nunn-Brooks, Lindsey</creatorcontrib><creatorcontrib>Michael, Robin</creatorcontrib><creatorcontrib>Ravitz, Lea B.</creatorcontrib><creatorcontrib>Kordick, Dorsey</creatorcontrib><creatorcontrib>Lappin, Michael R.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of feline medicine and surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Nunn-Brooks, Lindsey</au><au>Michael, Robin</au><au>Ravitz, Lea B.</au><au>Kordick, Dorsey</au><au>Lappin, Michael R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy of a single dose of an otic ivermectin preparation or selamectin for the treatment of Otodectes cynotis infestation in naturally infected cats</atitle><jtitle>Journal of feline medicine and surgery</jtitle><addtitle>J Feline Med Surg</addtitle><date>2011-08-01</date><risdate>2011</risdate><volume>13</volume><issue>8</issue><spage>622</spage><epage>624</epage><pages>622-624</pages><issn>1098-612X</issn><issn>1532-2750</issn><eissn>1532-2750</eissn><abstract>Otodectes cynotis infestation is common in kittens housed in crowded environments like animal shelters. It is unknown how rapidly
O cynotis is killed within the first 72
h of treatment with currently available products. Kittens ≥4 weeks of age with live
O cynotis in both ears (AU) were administered 0.5
ml of 0.01% ivermectin otic suspension (Acarexx; Idexx Pharmaceuticals) once, AU or selamectin (Revolution; Pfizer Animal Health) once, on the skin following the manufacturer’s instructions. Repeat microscopic examination was performed on individual ears based on a randomization schedule during the 72
h after treatment. There was no evidence of toxicity with either drug and administration of 0.01% ivermectin significantly reduced the time to live mite-free status compared to selamectin. Both drugs have an effect against
O cynotis as early as 10–12
h after administration with an increasing effect over time.</abstract><cop>London, England</cop><pub>Elsevier Ltd</pub><pmid>21536472</pmid><doi>10.1016/j.jfms.2011.03.003</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1098-612X |
| ispartof | Journal of feline medicine and surgery, 2011-08, Vol.13 (8), p.622-624 |
| issn | 1098-612X 1532-2750 1532-2750 |
| language | eng |
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| source | Sage Journals GOLD Open Access 2024 |
| subjects | Animals Antiparasitic Agents - administration & dosage Cat Diseases - drug therapy Cat Diseases - parasitology Cats Ear - parasitology Ivermectin - administration & dosage Ivermectin - analogs & derivatives Mite Infestations - drug therapy Mite Infestations - veterinary Short Communication Survival Analysis Treatment Outcome |
| title | Efficacy of a single dose of an otic ivermectin preparation or selamectin for the treatment of Otodectes cynotis infestation in naturally infected cats |
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