Loss of p73 Expression Contributes to Chronic Obstructive Pulmonary Disease

Multiciliated cell (MCC) loss and/or dysfunction is common in the small airways of patients with chronic obstructive pulmonary disease (COPD), but it is unclear if this contributes to COPD lung pathology. To determine if loss of p73 causes a COPD-like phenotype in mice and explore whether smoking or...

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