Tirzepatide Immunogenicity on Pharmacokinetics, Efficacy, and Safety: Analysis of Data From Phase 3 Studies

Abstract Context Antidrug antibodies (ADA) can potentially affect drug pharmacokinetics, safety, and efficacy. Objective This work aimed to evaluate treatment-emergent (TE) ADA in tirzepatide (TZP)-treated participants across 7 phase 3 trials and their potential effect on pharmacokinetics, efficacy,...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2024-01, Vol.109 (2), p.361-369
Hauptverfasser:	Mullins, Garrett R, Hodsdon, Michael E, Li, Ying Grace, Anglin, Greg, Urva, Shweta, Schneck, Karen, Bardos, Jennifer N, Martins, Ricardo Fonseca, Brown, Katelyn, Calderon, Boris
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical
Online-Zugang:	Volltext
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