Targeting the activin receptor 1C on CD4+ T cells for cancer immunotherapy

Activins, members of the TGF-beta superfamily, have been isolated and identified in the endocrine system, but have not been substantially investigated in the context of the immune system and endocrine-unrelated cancers. Here, we demonstrated that tumor-bearing mice had elevated systemic activin leve...

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Veröffentlicht in:	Oncoimmunology 2024-12, Vol.13 (1), p.2297503-2297503
Hauptverfasser:	Zheng, Ying, Lebid, Andriana, Chung, Liam, Fu, Juan, Wang, Xiaoxu, Otrocol, Andrea, Zarif, Jelani C., Yu, Hong, Llosa, Nicolas J., Pardoll, Drew M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Activin Acvr1c Alk7 cancer immunotherapy Foxp3 iTregs Original Research TILs
Online-Zugang:	Volltext
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