Quantitative Pupillometry: Not a Clear Predictor of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage
[...]like many observed phenomena, accurate identification of nuanced pupillary abnormalities requires highly trained assessors, which can limit the reliability of the measurement [2, 3] and its full potential as a noninvasive longitudinal biomarker. [5] treated NPi as a dichotomous rather than a co...
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| Veröffentlicht in: | Neurocritical care 2023-08, Vol.39 (1), p.34-35 |
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| creator | Ong, Charlene J. |
| description | [...]like many observed phenomena, accurate identification of nuanced pupillary abnormalities requires highly trained assessors, which can limit the reliability of the measurement [2, 3] and its full potential as a noninvasive longitudinal biomarker. [5] treated NPi as a dichotomous rather than a continuous variable, which may have more clinical use but may not capture a more nuanced association. [...]the frequency with which pupil observations were taken (every 8 h) may not have been sufficient to capture pupil abnormalities that occur close in time to DCI. [...]although the authors hypothesized that the pupillary light reflex could be affected by ischemic injury due to DCI after SAH, the mechanism by which the hypothesized decreased reactivity is unclear. |
| doi_str_mv | 10.1007/s12028-023-01709-1 |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings; ProQuest Central |
| subjects | Biomarkers Brain Ischemia - etiology Cardiac arrest Cerebral Infarction Conflicts of interest Critical Care Medicine Hemorrhage Humans Intensive Internal Medicine Invited Commentary Ischemia Medicine Medicine & Public Health Neurology Neurosurgery Stroke Subarachnoid Hemorrhage - complications |
| title | Quantitative Pupillometry: Not a Clear Predictor of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage |
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