Multiomics identifies metabolic subtypes based on fatty acid degradation allocating personalized treatment in hepatocellular carcinoma

Molecular classification is a promising tool for prognosis prediction and optimizing precision therapy for HCC. Here, we aimed to develop a molecular classification of HCC based on the fatty acid degradation (FAD) pathway, fully characterize it, and evaluate its ability in guiding personalized thera...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2024-02, Vol.79 (2), p.289-306
Hauptverfasser:	Li, Binghua, Li, Yunzheng, Zhou, Huajun, Xu, Yanchao, Cao, Yajuan, Cheng, Chunxiao, Peng, Jin, Li, Huan, Zhang, Laizhu, Su, Ke, Xu, Zhu, Hu, Yue, Lu, Jiaming, Lu, Yijun, Qian, Liyuan, Wang, Ye, Zhang, Yuchen, Liu, Qi, Xie, Yuanyuan, Guo, Sheng, Mehal, Wajahat Z, Yu, Decai
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - genetics Chemoembolization, Therapeutic Fatty Acids Humans Liver Neoplasms - drug therapy Liver Neoplasms - genetics Mice Multiomics Original : Liver Cancer Precision Medicine Sorafenib - therapeutic use Tumor Microenvironment
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