Tenofovir Activation Is Diminished in the Brain and Liver of Creatine Kinase Brain-Type Knockout Mice

Tenofovir (TFV) is a nucleotide reverse transcriptase inhibitor prescribed for the treatment and prevention of human immunodeficiency virus infection and the treatment of chronic hepatitis B virus infection. Here, we demonstrate that creatine kinase brain-type (CKB) can form tenofovir-diphosphate (T...

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Veröffentlicht in:	ACS pharmacology & translational science 2024-01, Vol.7 (1), p.222-235
Hauptverfasser:	Eberhard, Colten D., Mosher, Eric P., Bumpus, Namandjé N., Orsburn, Benjamin C.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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