Comprehensive analysis of the proximity-dependent nuclear interactome for the oncoprotein NOTCH1 in live cells

Notch signaling plays a critical role in cell fate decisions in all cell types. Furthermore, gain-of-function mutations in NOTCH1 have been uncovered in many human cancers. Disruption of Notch signaling has recently emerged as an attractive disease treatment strategy. However, the nuclear interactio...

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Veröffentlicht in:	The Journal of biological chemistry 2024-01, Vol.300 (1), p.105522-105522, Article 105522
Hauptverfasser:	Torres, Haydee M, Fang, Fang, May, Danielle G, Bosshardt, Paige, Hinojosa, Leetoria, Roux, Kyle J, Tao, Jianning
Format:	Artikel
Sprache:	eng
Schlagworte:	Methods and Resources
Online-Zugang:	Volltext
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