A Systematic Evaluation of Machine Learning–Based Biomarkers for Major Depressive Disorder

IMPORTANCE: Biological psychiatry aims to understand mental disorders in terms of altered neurobiological pathways. However, for one of the most prevalent and disabling mental disorders, major depressive disorder (MDD), no informative biomarkers have been identified. OBJECTIVE: To evaluate whether m...

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Veröffentlicht in:	JAMA psychiatry (Chicago, Ill.) Ill.), 2024-04, Vol.81 (4), p.386-395
Hauptverfasser:	Winter, Nils R, Blanke, Julian, Leenings, Ramona, Ernsting, Jan, Fisch, Lukas, Sarink, Kelvin, Barkhau, Carlotta, Emden, Daniel, Thiel, Katharina, Flinkenflügel, Kira, Winter, Alexandra, Goltermann, Janik, Meinert, Susanne, Dohm, Katharina, Repple, Jonathan, Gruber, Marius, Leehr, Elisabeth J, Opel, Nils, Grotegerd, Dominik, Redlich, Ronny, Nitsch, Robert, Bauer, Jochen, Heindel, Walter, Gross, Joachim, Risse, Benjamin, Andlauer, Till F. M, Forstner, Andreas J, Nöthen, Markus M, Rietschel, Marcella, Hofmann, Stefan G, Pfarr, Julia-Katharina, Teutenberg, Lea, Usemann, Paula, Thomas-Odenthal, Florian, Wroblewski, Adrian, Brosch, Katharina, Stein, Frederike, Jansen, Andreas, Jamalabadi, Hamidreza, Alexander, Nina, Straube, Benjamin, Nenadic, Igor, Kircher, Tilo, Dannlowski, Udo, Hahn, Tim
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Cohort Studies Comments Depressive Disorder, Major - diagnostic imaging Depressive Disorder, Major - pathology Diffusion Tensor Imaging Female Humans Magnetic Resonance Imaging Male Mental depression Neurobiology Neuroimaging Online First Original Investigation Psychiatry Reproducibility of Results
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