Interdisciplinary Rendez-Vous Approach in Endovascular Stroke Treatment: A New Concept to Accelerate Mechanical Thrombectomy in Primary Stroke Centers

Purpose Prompt endovascular treatment of patients with stroke due to intracranial Large Vessel Occlusion (LVO) is a major challenge in rural areas because neurointerventionalists are usually not available. As a result, treatment is delayed, and clinical outcomes are worse compared with patients prim...

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Veröffentlicht in:Cardiovascular and interventional radiology 2024-01, Vol.47 (1), p.109-114
Hauptverfasser: Krug, Nadja, Braun, Holger, Knez, Andreas, Auerbach, Holger, Bodenberger, Stephen, Eglseder, Bettina, Kirschke, Jan, Boeckh-Behrens, Tobias, Wunderlich, Silke, Henninger, Julia, Boy, Sandra, Renz, Martin, Sepp, Dominik, Zimmer, Claus, Maegerlein, Christian
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container_end_page 114
container_issue 1
container_start_page 109
container_title Cardiovascular and interventional radiology
container_volume 47
creator Krug, Nadja
Braun, Holger
Knez, Andreas
Auerbach, Holger
Bodenberger, Stephen
Eglseder, Bettina
Kirschke, Jan
Boeckh-Behrens, Tobias
Wunderlich, Silke
Henninger, Julia
Boy, Sandra
Renz, Martin
Sepp, Dominik
Zimmer, Claus
Maegerlein, Christian
description Purpose Prompt endovascular treatment of patients with stroke due to intracranial Large Vessel Occlusion (LVO) is a major challenge in rural areas because neurointerventionalists are usually not available. As a result, treatment is delayed, and clinical outcomes are worse compared with patients primarily treated in comprehensive stroke centers (CSC). To address this problem, we present a concept in which interdisciplinary, on-site endovascular treatment is performed in a Primary Stroke Center (PSC) by a team of interventional neuroradiologists and cardiologists: the Rendez-Vous approach. Methods Thirty-five patients with LVO who underwent interdisciplinary thrombectomy on-site at the PSC as part of the Rendez-Vous concept were compared with 72 patients who were transferred from a PSCs to the CSC for thrombectomy when diagnosed with LVO in terms of temporal sequences and clinical outcomes. Results Patients treated on-site at the PSC as part of the Rendez-Vous approach were managed as successfully and without an increase in complication rates compared with patients treated secondarily at a CSC (91.7% successful interventions in Rendez-Vous vs. 87.3% in control group, p  = 0.57). The time from diagnosis of LVO to groin puncture was reduced by mean 74.3 min with the Rendez-Vous concept ( p  
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As a result, treatment is delayed, and clinical outcomes are worse compared with patients primarily treated in comprehensive stroke centers (CSC). To address this problem, we present a concept in which interdisciplinary, on-site endovascular treatment is performed in a Primary Stroke Center (PSC) by a team of interventional neuroradiologists and cardiologists: the Rendez-Vous approach. Methods Thirty-five patients with LVO who underwent interdisciplinary thrombectomy on-site at the PSC as part of the Rendez-Vous concept were compared with 72 patients who were transferred from a PSCs to the CSC for thrombectomy when diagnosed with LVO in terms of temporal sequences and clinical outcomes. Results Patients treated on-site at the PSC as part of the Rendez-Vous approach were managed as successfully and without an increase in complication rates compared with patients treated secondarily at a CSC (91.7% successful interventions in Rendez-Vous vs. 87.3% in control group, p  = 0.57). The time from diagnosis of LVO to groin puncture was reduced by mean 74.3 min with the Rendez-Vous concept ( p  &lt; 0.01). Regarding the clinical outcome, a functionally independent status was achieved in 45.5% in the Rendez-Vous group and in 22.6% in the control group ( p  = 0.029). Conclusion Thanks to interdisciplinary teamwork between cardiology and interventional neuroradiology in local PSCs, times to successful reperfusion can be reduced. This has a potentially positive impact on the clinical outcome of stroke patients. Graphical Abstract</description><identifier>ISSN: 0174-1551</identifier><identifier>EISSN: 1432-086X</identifier><identifier>DOI: 10.1007/s00270-023-03610-y</identifier><identifier>PMID: 37989788</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Brain Ischemia - etiology ; Cardiology ; Cardiovascular system ; Clinical outcomes ; Endovascular Procedures - adverse effects ; Humans ; Imaging ; Interdisciplinary aspects ; Medicine ; Medicine &amp; Public Health ; Neuroimaging ; Nuclear Medicine ; Onsite ; Patients ; Radiology ; Reperfusion ; Retrospective Studies ; Rural areas ; Short Communication ; Stroke ; Stroke - diagnostic imaging ; Stroke - surgery ; Stroke/Neurointerventions ; Thrombectomy ; Treatment Outcome ; Ultrasound</subject><ispartof>Cardiovascular and interventional radiology, 2024-01, Vol.47 (1), p.109-114</ispartof><rights>The Author(s) 2023</rights><rights>2023. The Author(s).</rights><rights>The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-ec67ee46b0835c5082924e7f2807a8b37d848278e91282299a46c74fcb346d433</citedby><cites>FETCH-LOGICAL-c475t-ec67ee46b0835c5082924e7f2807a8b37d848278e91282299a46c74fcb346d433</cites><orcidid>0000-0003-4885-7671</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00270-023-03610-y$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00270-023-03610-y$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37989788$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Krug, Nadja</creatorcontrib><creatorcontrib>Braun, Holger</creatorcontrib><creatorcontrib>Knez, Andreas</creatorcontrib><creatorcontrib>Auerbach, Holger</creatorcontrib><creatorcontrib>Bodenberger, Stephen</creatorcontrib><creatorcontrib>Eglseder, Bettina</creatorcontrib><creatorcontrib>Kirschke, Jan</creatorcontrib><creatorcontrib>Boeckh-Behrens, Tobias</creatorcontrib><creatorcontrib>Wunderlich, Silke</creatorcontrib><creatorcontrib>Henninger, Julia</creatorcontrib><creatorcontrib>Boy, Sandra</creatorcontrib><creatorcontrib>Renz, Martin</creatorcontrib><creatorcontrib>Sepp, Dominik</creatorcontrib><creatorcontrib>Zimmer, Claus</creatorcontrib><creatorcontrib>Maegerlein, Christian</creatorcontrib><title>Interdisciplinary Rendez-Vous Approach in Endovascular Stroke Treatment: A New Concept to Accelerate Mechanical Thrombectomy in Primary Stroke Centers</title><title>Cardiovascular and interventional radiology</title><addtitle>Cardiovasc Intervent Radiol</addtitle><addtitle>Cardiovasc Intervent Radiol</addtitle><description>Purpose Prompt endovascular treatment of patients with stroke due to intracranial Large Vessel Occlusion (LVO) is a major challenge in rural areas because neurointerventionalists are usually not available. As a result, treatment is delayed, and clinical outcomes are worse compared with patients primarily treated in comprehensive stroke centers (CSC). To address this problem, we present a concept in which interdisciplinary, on-site endovascular treatment is performed in a Primary Stroke Center (PSC) by a team of interventional neuroradiologists and cardiologists: the Rendez-Vous approach. Methods Thirty-five patients with LVO who underwent interdisciplinary thrombectomy on-site at the PSC as part of the Rendez-Vous concept were compared with 72 patients who were transferred from a PSCs to the CSC for thrombectomy when diagnosed with LVO in terms of temporal sequences and clinical outcomes. Results Patients treated on-site at the PSC as part of the Rendez-Vous approach were managed as successfully and without an increase in complication rates compared with patients treated secondarily at a CSC (91.7% successful interventions in Rendez-Vous vs. 87.3% in control group, p  = 0.57). The time from diagnosis of LVO to groin puncture was reduced by mean 74.3 min with the Rendez-Vous concept ( p  &lt; 0.01). Regarding the clinical outcome, a functionally independent status was achieved in 45.5% in the Rendez-Vous group and in 22.6% in the control group ( p  = 0.029). Conclusion Thanks to interdisciplinary teamwork between cardiology and interventional neuroradiology in local PSCs, times to successful reperfusion can be reduced. This has a potentially positive impact on the clinical outcome of stroke patients. 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As a result, treatment is delayed, and clinical outcomes are worse compared with patients primarily treated in comprehensive stroke centers (CSC). To address this problem, we present a concept in which interdisciplinary, on-site endovascular treatment is performed in a Primary Stroke Center (PSC) by a team of interventional neuroradiologists and cardiologists: the Rendez-Vous approach. Methods Thirty-five patients with LVO who underwent interdisciplinary thrombectomy on-site at the PSC as part of the Rendez-Vous concept were compared with 72 patients who were transferred from a PSCs to the CSC for thrombectomy when diagnosed with LVO in terms of temporal sequences and clinical outcomes. Results Patients treated on-site at the PSC as part of the Rendez-Vous approach were managed as successfully and without an increase in complication rates compared with patients treated secondarily at a CSC (91.7% successful interventions in Rendez-Vous vs. 87.3% in control group, p  = 0.57). The time from diagnosis of LVO to groin puncture was reduced by mean 74.3 min with the Rendez-Vous concept ( p  &lt; 0.01). Regarding the clinical outcome, a functionally independent status was achieved in 45.5% in the Rendez-Vous group and in 22.6% in the control group ( p  = 0.029). Conclusion Thanks to interdisciplinary teamwork between cardiology and interventional neuroradiology in local PSCs, times to successful reperfusion can be reduced. This has a potentially positive impact on the clinical outcome of stroke patients. Graphical Abstract</abstract><cop>New York</cop><pub>Springer US</pub><pmid>37989788</pmid><doi>10.1007/s00270-023-03610-y</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-4885-7671</orcidid><oa>free_for_read</oa></addata></record>
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source MEDLINE; SpringerLink Journals - AutoHoldings
subjects Brain Ischemia - etiology
Cardiology
Cardiovascular system
Clinical outcomes
Endovascular Procedures - adverse effects
Humans
Imaging
Interdisciplinary aspects
Medicine
Medicine & Public Health
Neuroimaging
Nuclear Medicine
Onsite
Patients
Radiology
Reperfusion
Retrospective Studies
Rural areas
Short Communication
Stroke
Stroke - diagnostic imaging
Stroke - surgery
Stroke/Neurointerventions
Thrombectomy
Treatment Outcome
Ultrasound
title Interdisciplinary Rendez-Vous Approach in Endovascular Stroke Treatment: A New Concept to Accelerate Mechanical Thrombectomy in Primary Stroke Centers
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