Single-drug versus combination antimicrobial therapy in critically ill patients with hospital-acquired pneumonia and ventilator-associated pneumonia due to Gram-negative pathogens: a multicenter retrospective cohort study

In this study including 391 critically ill patients with nosocomial pneumonia due to Gram-negative pathogens, combination therapy was not associated with a reduced hazard of death at Day 28 or a greater likelihood of clinical cure at Day 14. No over-risk of AKI was observed in patients receiving com...

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Veröffentlicht in:	Critical care (London, England) England), 2024-01, Vol.28 (1), p.10-10, Article 10
Hauptverfasser:	Barbier, François, Dupuis, Claire, Buetti, Niccolò, Schwebel, Carole, Azoulay, Élie, Argaud, Laurent, Cohen, Yves, Hong Tuan Ha, Vivien, Gainnier, Marc, Siami, Shidasp, Forel, Jean-Marie, Adrie, Christophe, de Montmollin, Étienne, Reignier, Jean, Ruckly, Stéphane, Zahar, Jean-Ralph, Timsit, Jean-François
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-infective agents Antibiotics Bacteria Blood Body temperature Control Disease control Dosage and administration Drug resistance Drug resistance in microorganisms Drug therapy Gram-negative bacteria Health aspects Identification and classification Infections Life Sciences Medical research Medicine, Experimental Mortality Pathogenic microorganisms Pathogens Pneumonia Prevention Risk factors Sepsis Septic shock Ventilators
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