Identification of potential drug candidates to treat gastritis and associated oxidative stress based on some novel 2-aryl-1H-naphtho[2,3-d]imidazole: synthesis, in vitro and in silico analysis

To identify potential scaffolds to treat gastritis and oxidative stress, 2-aryl-1H-naphtho[2,3-d]imidazole derivatives (1–15) were synthesized. The synthesis was conveniently carried out by condensing 2,3-diaminonaphthalene with variously substituted aldehydes to yield 15 new 2-aryl-1H-naphtho[2,3-d...

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Veröffentlicht in:	RSC advances 2024-01, Vol.14 (1), p.529-537
Hauptverfasser:	Sultana, Amina, Wahab, Aneela, Fareed, Ghulam, Rafiq, Hamna, Khalid Mohammed Khan, Lateef, Mehreen, Fareed, Nazia, Hussain, Shafqat, Sikander Khan Sherwani
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehydes Antioxidants Aromatic compounds Binding Chemical synthesis Chemistry Imidazole Jack beans Molecular docking NMR Nuclear magnetic resonance Oxidative stress
Online-Zugang:	Volltext
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