Connexin 36 Mediated Intercellular Endoplasmic Reticulum Stress Transmission Induces SSTA Resistance in Growth Hormone Pituitary Adenoma

Somatostatin analogues (SSTA) are first-line pharmacological treatment choice for acromegaly, which received satisfying tumor shrinkage and normalization of growth hormone. However, there are still patients unresponsive to SSTA, and the underline mechanism remains unknown. Besides, there is no evide...

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Veröffentlicht in:International journal of biological sciences 2024, Vol.20 (2), p.801-817
Hauptverfasser: Wang, Zihan, Lei, Zhuowei, Wang, Quanji, Jiang, Qian, Zhang, Zhuo, Liu, Xiaojin, Xing, Biao, Li, Sihan, Guo, Xiang, Liu, Yanchao, Li, Xingbo, Qi, Yiwei, Shu, Kai, Zhang, Huaqiu, Huang, Yimin, Lei, Ting
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Sprache:eng
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