Morphea Involving the Lips and Gingiva: A Rare Case Report
Morphea is a subtype of scleroderma that does not involve Raynaud's phenomenon or internal organ involvement. It is a connective tissue disease that features the excessive deposition of collagen in the dermis and subcutaneous tissue, leading to a thickening of the dermis and subcutaneous tissue...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2023-12, Vol.15 (12), p.e51202 |
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| creator | Albagieh, Hamad Alshagroud, Rana S Aladnan, Abdullah M Aldosari, Bader Alburaykan, Yara B Almashham, Lama Y Alqasem, Afyaa A Alyahya, Areen A Aboheimed, Nada I |
| description | Morphea is a subtype of scleroderma that does not involve Raynaud's phenomenon or internal organ involvement. It is a connective tissue disease that features the excessive deposition of collagen in the dermis and subcutaneous tissue, leading to a thickening of the dermis and subcutaneous tissue, eventually forming a scar-like lesion. We represent a 19-year-old male Saudi patient displaying a white patch on the marginal gingiva of tooth #21 and multiple yellowish papules on the outer surface of the lip. Both teeth #21 and #22 have experienced recession and bone loss. The patient's clinical history and histopathology revealed characteristic features of localized scleroderma. A treatment was proposed involving immunosuppressants, methotrexate, and pimecrolimus cream along with topical corticosteroids and excimer laser therapy (308 nm). The patient followed the treatment plan for a full month and the white patch quickly improved for the patient. Afterward, the patient has been taking only methotrexate with a significant but gradual improvement. In this paper, we discuss the differential diagnosis to be considered and present an unusual occurrence of localized scleroderma in the oral cavity. |
| doi_str_mv | 10.7759/cureus.51202 |
| format | Article |
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It is a connective tissue disease that features the excessive deposition of collagen in the dermis and subcutaneous tissue, leading to a thickening of the dermis and subcutaneous tissue, eventually forming a scar-like lesion. We represent a 19-year-old male Saudi patient displaying a white patch on the marginal gingiva of tooth #21 and multiple yellowish papules on the outer surface of the lip. Both teeth #21 and #22 have experienced recession and bone loss. The patient's clinical history and histopathology revealed characteristic features of localized scleroderma. A treatment was proposed involving immunosuppressants, methotrexate, and pimecrolimus cream along with topical corticosteroids and excimer laser therapy (308 nm). The patient followed the treatment plan for a full month and the white patch quickly improved for the patient. Afterward, the patient has been taking only methotrexate with a significant but gradual improvement. In this paper, we discuss the differential diagnosis to be considered and present an unusual occurrence of localized scleroderma in the oral cavity.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.51202</identifier><identifier>PMID: 38155978</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Blood vessels ; Case reports ; Connective tissue ; Dentistry ; Oral hygiene ; Oral Medicine ; Pathology ; Scleroderma ; Skin diseases ; Steroids ; Teeth</subject><ispartof>Curēus (Palo Alto, CA), 2023-12, Vol.15 (12), p.e51202</ispartof><rights>Copyright © 2023, Albagieh et al.</rights><rights>Copyright © 2023, Albagieh et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2023, Albagieh et al. 2023 Albagieh et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c267t-376f2f865a8bddeaa524ed566d250099338732c2539f462b5a63346d0d350cbb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10754225/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10754225/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38155978$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Albagieh, Hamad</creatorcontrib><creatorcontrib>Alshagroud, Rana S</creatorcontrib><creatorcontrib>Aladnan, Abdullah M</creatorcontrib><creatorcontrib>Aldosari, Bader</creatorcontrib><creatorcontrib>Alburaykan, Yara B</creatorcontrib><creatorcontrib>Almashham, Lama Y</creatorcontrib><creatorcontrib>Alqasem, Afyaa A</creatorcontrib><creatorcontrib>Alyahya, Areen A</creatorcontrib><creatorcontrib>Aboheimed, Nada I</creatorcontrib><title>Morphea Involving the Lips and Gingiva: A Rare Case Report</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Morphea is a subtype of scleroderma that does not involve Raynaud's phenomenon or internal organ involvement. 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In this paper, we discuss the differential diagnosis to be considered and present an unusual occurrence of localized scleroderma in the oral cavity.</description><subject>Blood vessels</subject><subject>Case reports</subject><subject>Connective tissue</subject><subject>Dentistry</subject><subject>Oral hygiene</subject><subject>Oral Medicine</subject><subject>Pathology</subject><subject>Scleroderma</subject><subject>Skin diseases</subject><subject>Steroids</subject><subject>Teeth</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpVkM1Lw0AQxRdRbIm9eZYFr6buR_YjvUgpWgsVoeh52WQ3bUqbjbtJwP_eaKvU0wwzjzdvfgBcYzQWgqX3eettG8YME0TOwJBgLmOJZXJ-0g_AKIQtQggjQZBAl2BAJWYsFXIIJi_O1xur4aLq3K4rqzVsNhYuyzpAXRk47ydlpydwClfaWzjTwcKVrZ1vrsBFoXfBjo41Au9Pj2-z53j5Ol_Mpss4J1w0MRW8IIXkTMvMGKs1I4k1jHNDGEJpSqkUlOSE0bRIOMmY5pQm3CBDGcqzjEbg4eBbt9nemtxWjdc7Vftyr_2ncrpU_zdVuVFr16n-X5aQ3jgCt0cH7z5aGxq1da2v-tCKpEgiLmSfIwJ3B1XuXQjeFn8nMFLftNWBtvqh3ctvTmP9iX_Z0i_ctXpM</recordid><startdate>20231227</startdate><enddate>20231227</enddate><creator>Albagieh, Hamad</creator><creator>Alshagroud, Rana S</creator><creator>Aladnan, Abdullah M</creator><creator>Aldosari, Bader</creator><creator>Alburaykan, Yara B</creator><creator>Almashham, Lama Y</creator><creator>Alqasem, Afyaa A</creator><creator>Alyahya, Areen A</creator><creator>Aboheimed, Nada I</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PKEHL</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>5PM</scope></search><sort><creationdate>20231227</creationdate><title>Morphea Involving the Lips and Gingiva: A Rare Case Report</title><author>Albagieh, Hamad ; Alshagroud, Rana S ; Aladnan, Abdullah M ; Aldosari, Bader ; Alburaykan, Yara B ; Almashham, Lama Y ; Alqasem, Afyaa A ; Alyahya, Areen A ; Aboheimed, Nada I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c267t-376f2f865a8bddeaa524ed566d250099338732c2539f462b5a63346d0d350cbb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Blood vessels</topic><topic>Case reports</topic><topic>Connective tissue</topic><topic>Dentistry</topic><topic>Oral hygiene</topic><topic>Oral Medicine</topic><topic>Pathology</topic><topic>Scleroderma</topic><topic>Skin diseases</topic><topic>Steroids</topic><topic>Teeth</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Albagieh, Hamad</creatorcontrib><creatorcontrib>Alshagroud, Rana S</creatorcontrib><creatorcontrib>Aladnan, Abdullah M</creatorcontrib><creatorcontrib>Aldosari, Bader</creatorcontrib><creatorcontrib>Alburaykan, Yara B</creatorcontrib><creatorcontrib>Almashham, Lama Y</creatorcontrib><creatorcontrib>Alqasem, Afyaa A</creatorcontrib><creatorcontrib>Alyahya, Areen A</creatorcontrib><creatorcontrib>Aboheimed, Nada I</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Albagieh, Hamad</au><au>Alshagroud, Rana S</au><au>Aladnan, Abdullah M</au><au>Aldosari, Bader</au><au>Alburaykan, Yara B</au><au>Almashham, Lama Y</au><au>Alqasem, Afyaa A</au><au>Alyahya, Areen A</au><au>Aboheimed, Nada I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Morphea Involving the Lips and Gingiva: A Rare Case Report</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2023-12-27</date><risdate>2023</risdate><volume>15</volume><issue>12</issue><spage>e51202</spage><pages>e51202-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Morphea is a subtype of scleroderma that does not involve Raynaud's phenomenon or internal organ involvement. It is a connective tissue disease that features the excessive deposition of collagen in the dermis and subcutaneous tissue, leading to a thickening of the dermis and subcutaneous tissue, eventually forming a scar-like lesion. We represent a 19-year-old male Saudi patient displaying a white patch on the marginal gingiva of tooth #21 and multiple yellowish papules on the outer surface of the lip. Both teeth #21 and #22 have experienced recession and bone loss. The patient's clinical history and histopathology revealed characteristic features of localized scleroderma. A treatment was proposed involving immunosuppressants, methotrexate, and pimecrolimus cream along with topical corticosteroids and excimer laser therapy (308 nm). The patient followed the treatment plan for a full month and the white patch quickly improved for the patient. Afterward, the patient has been taking only methotrexate with a significant but gradual improvement. 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| source | PubMed Central; PubMed Central Open Access |
| subjects | Blood vessels Case reports Connective tissue Dentistry Oral hygiene Oral Medicine Pathology Scleroderma Skin diseases Steroids Teeth |
| title | Morphea Involving the Lips and Gingiva: A Rare Case Report |
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