Preservation of β-cell Function in Pancreatic Insufficient Cystic Fibrosis With Highly Effective CFTR Modulator Therapy

Abstract Context Elexacaftor/tezacaftor/ivacaftor (ETI; Trikafta) enhances aberrant cystic fibrosis transmembrane conductance regulator function and may improve the insulin secretory defects associated with a deterioration in clinical outcomes in pancreatic insufficient cystic fibrosis (PI-CF). Obje...

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Veröffentlicht in:The journal of clinical endocrinology and metabolism 2023-12, Vol.109 (1), p.151-160
Hauptverfasser: Flatt, Anneliese J, Sheikh, Saba, Peleckis, Amy J, Alvarado, Paola, Hadjiliadis, Denis, Stefanovski, Darko, Gallop, Robert J, Rubenstein, Ronald C, Kelly, Andrea, Rickels, Michael R
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Sprache:eng
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