A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk

•PR can be predicted from scattergrams generated by hematology analyzers of a type that is in widespread clinical use.•Genetic analysis of predicted PR reveals associations with the risk of thrombotic diseases, including stroke. [Display omitted] Genetic studies of platelet reactivity (PR) phenotype...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (22), p.1895-1908
Hauptverfasser:	Verdier, Hippolyte, Thomas, Patrick, Batista, Joana, Kempster, Carly, McKinney, Harriet, Gleadall, Nicholas, Danesh, John, Mumford, Andrew, Heemskerk, Johan, Ouwehand, Willem H., Downes, Kate, Astle, William J., Turro, Ernest
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Cell Count Blood Platelets Genome-Wide Association Study Humans Platelet Aggregation Inhibitors - pharmacology Platelets and Thrombopoiesis Thrombosis - genetics
Online-Zugang:	Volltext
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