PRKAG2.2 is essential for FoxA1 + regulatory T cell differentiation and metabolic rewiring distinct from FoxP3 + regulatory T cells

Forkhead box A1 (FoxA1) regulatory T cells (T ) exhibit distinct characteristics from FoxP3 T while equally effective in exerting anti-inflammatory properties. The role of FoxP3 T in vivo has been challenged, motivating a better understanding of other T in modulating hyperactive immune responses. Fo...

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Veröffentlicht in:	Science advances 2023-12, Vol.9 (51), p.eadj8442-eadj8442
Hauptverfasser:	Mandatori, Sara, Liu, Yawei, Marturia-Navarro, Joana, Hadi, Mahdieh, Henriksen, Kristine, Zheng, Jin, Rasmussen, Louise Munk, Rizza, Salvatore, Kaestner, Klaus H, Issazadeh-Navikas, Shohreh
Format:	Artikel
Sprache:	eng
Schlagworte:	AMP-Activated Protein Kinases - metabolism Anti-Inflammatory Agents - metabolism Biomedicine and Life Sciences Cell Differentiation Gene Expression Regulation Immunology SciAdv r-articles T-Lymphocytes, Regulatory
Online-Zugang:	Volltext
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