Molecular detection of pre-ribosomal RNAs of Mycobacterium bovis bacille Calmette-Guérin and Mycobacterium tuberculosis to enhance pre-clinical tuberculosis drug and vaccine development

Efforts are underway globally to develop effective vaccines and drugs against M. tuberculosis (Mtb) to reduce the morbidity and mortality of tuberculosis. Improving detection of slow-growing mycobacteria could simplify and accelerate efficacy studies of vaccines and drugs in animal models and human...

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Veröffentlicht in:	Diagnostic microbiology and infectious disease 2024-01, Vol.108 (1), p.116106, Article 116106
Hauptverfasser:	Chang, Ming, Venkatasubramanian, Sambasivan, Barrett, Holly, Urdahl, Kevin B, Weigel, Kris M, Cangelosi, Gerard A, Shah, Javeed A, Saha, Aparajita, Feng, Libing, Adams, Kristin N, Sherman, David R, Smith, Nahum, Seshadri, Chetan, Kublin, James G, Murphy, Sean C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BCG Vaccine Biomarkers Humans Mice Mycobacterium bovis - genetics Mycobacterium tuberculosis - genetics Original RNA Precursors Tuberculosis - diagnosis Tuberculosis - prevention & control Vaccine Development
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