Genetic characterization and description of Leishmania (Leishmania) ellisi sp. nov.: a new human-infecting species from the USA
In a 2018 report, an unusual case of cutaneous leishmaniasis was described in a 72-year-old female patient residing in Arizona, United States of America (USA). Preliminary analysis of the 18S rDNA and glyceraldehyde-3-phosphate dehydrogenase genes supported the conclusion that the Leishmania strain...
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| Veröffentlicht in: | Parasitology research (1987) 2024-01, Vol.123 (1), p.52-52, Article 52 |
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| container_title | Parasitology research (1987) |
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| creator | Sapp, Sarah G. H. Low, Ross Nine, Gabriela Nascimento, Fernanda S. Qvarnstrom, Yvonne Barratt, Joel L. N. |
| description | In a 2018 report, an unusual case of cutaneous leishmaniasis was described in a 72-year-old female patient residing in Arizona, United States of America (USA). Preliminary analysis of the 18S rDNA and glyceraldehyde-3-phosphate dehydrogenase genes supported the conclusion that the
Leishmania
strain (strain 218-L139) isolated from this case was a novel species, though a complete taxonomic description was not provided. Identification of
Leishmania
at the species level is critical for clinical management and epidemiologic investigations so it is important that novel human-infecting species are characterized taxonomically and assigned a unique scientific name compliant with the ICZN code. Therefore, we sought to provide a complete taxonomic description of
Leishmania
strain 218-L139. Phylogenetic analysis of several nuclear loci and partial maxicircle genome sequences supported its position within the subgenus
Leishmania
and further clarified the distinctness of this new species. Morphological characterization of cultured promastigotes and amastigotes from the original case material is also provided. Thus, we conclude that
Leishmania
(
Leishmania
)
ellisi
is a new cause of autochthonous cutaneous leishmaniasis in the USA. |
| doi_str_mv | 10.1007/s00436-023-08034-8 |
| format | Article |
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Leishmania
strain (strain 218-L139) isolated from this case was a novel species, though a complete taxonomic description was not provided. Identification of
Leishmania
at the species level is critical for clinical management and epidemiologic investigations so it is important that novel human-infecting species are characterized taxonomically and assigned a unique scientific name compliant with the ICZN code. Therefore, we sought to provide a complete taxonomic description of
Leishmania
strain 218-L139. Phylogenetic analysis of several nuclear loci and partial maxicircle genome sequences supported its position within the subgenus
Leishmania
and further clarified the distinctness of this new species. Morphological characterization of cultured promastigotes and amastigotes from the original case material is also provided. Thus, we conclude that
Leishmania
(
Leishmania
)
ellisi
is a new cause of autochthonous cutaneous leishmaniasis in the USA.</description><identifier>ISSN: 0932-0113</identifier><identifier>ISSN: 1432-1955</identifier><identifier>EISSN: 1432-1955</identifier><identifier>DOI: 10.1007/s00436-023-08034-8</identifier><identifier>PMID: 38099974</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Amastigotes ; Arizona ; Biomedical and Life Sciences ; Biomedicine ; Cutaneous leishmaniasis ; Epidemiology ; females ; Genetic aspects ; genome ; Genomes ; Genomics ; Glyceraldehyde-3-phosphate dehydrogenase ; Immunology ; Leishmania ; Leishmaniasis ; Medical Microbiology ; Microbiology ; New species ; Parasitic diseases ; patients ; Phosphates ; Phylogeny ; Promastigotes ; species ; subgenus ; taxon descriptions ; Taxonomy</subject><ispartof>Parasitology research (1987), 2024-01, Vol.123 (1), p.52-52, Article 52</ispartof><rights>This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023</rights><rights>2023. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.</rights><rights>COPYRIGHT 2024 Springer</rights><rights>This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c526t-e30b1b95b4847183895b53359266932a64086eb5544cf44b2be2d671b279b6de3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00436-023-08034-8$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00436-023-08034-8$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38099974$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sapp, Sarah G. H.</creatorcontrib><creatorcontrib>Low, Ross</creatorcontrib><creatorcontrib>Nine, Gabriela</creatorcontrib><creatorcontrib>Nascimento, Fernanda S.</creatorcontrib><creatorcontrib>Qvarnstrom, Yvonne</creatorcontrib><creatorcontrib>Barratt, Joel L. N.</creatorcontrib><title>Genetic characterization and description of Leishmania (Leishmania) ellisi sp. nov.: a new human-infecting species from the USA</title><title>Parasitology research (1987)</title><addtitle>Parasitol Res</addtitle><addtitle>Parasitol Res</addtitle><description>In a 2018 report, an unusual case of cutaneous leishmaniasis was described in a 72-year-old female patient residing in Arizona, United States of America (USA). Preliminary analysis of the 18S rDNA and glyceraldehyde-3-phosphate dehydrogenase genes supported the conclusion that the
Leishmania
strain (strain 218-L139) isolated from this case was a novel species, though a complete taxonomic description was not provided. Identification of
Leishmania
at the species level is critical for clinical management and epidemiologic investigations so it is important that novel human-infecting species are characterized taxonomically and assigned a unique scientific name compliant with the ICZN code. Therefore, we sought to provide a complete taxonomic description of
Leishmania
strain 218-L139. Phylogenetic analysis of several nuclear loci and partial maxicircle genome sequences supported its position within the subgenus
Leishmania
and further clarified the distinctness of this new species. Morphological characterization of cultured promastigotes and amastigotes from the original case material is also provided. Thus, we conclude that
Leishmania
(
Leishmania
)
ellisi
is a new cause of autochthonous cutaneous leishmaniasis in the USA.</description><subject>Amastigotes</subject><subject>Arizona</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cutaneous leishmaniasis</subject><subject>Epidemiology</subject><subject>females</subject><subject>Genetic aspects</subject><subject>genome</subject><subject>Genomes</subject><subject>Genomics</subject><subject>Glyceraldehyde-3-phosphate dehydrogenase</subject><subject>Immunology</subject><subject>Leishmania</subject><subject>Leishmaniasis</subject><subject>Medical Microbiology</subject><subject>Microbiology</subject><subject>New species</subject><subject>Parasitic diseases</subject><subject>patients</subject><subject>Phosphates</subject><subject>Phylogeny</subject><subject>Promastigotes</subject><subject>species</subject><subject>subgenus</subject><subject>taxon descriptions</subject><subject>Taxonomy</subject><issn>0932-0113</issn><issn>1432-1955</issn><issn>1432-1955</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><recordid>eNqFkk1v1DAQhiMEokvhD3BAlriUQxZ_J-FSrapSkFbiAD1bjjPZdbWxFzspggt_vdPd0qUIgXzwOPPMq8zMWxQvGZ0zSqu3mVIpdEm5KGlNhSzrR8WMScFL1ij1uJjRBmPKmDgqnuV8RSmrtJRPiyNR06ZpKjkrfl5AgNE74tY2WTdC8j_s6GMgNnSkg-yS3-7esSdL8Hk92OAtOTnEbwhsNj57krdzEuL1_B2xJMA3sp4wX_rQgxt9WGEenIdM-hQHMq6BXH5ePC-e9HaT4cXdfVxcvj__cvahXH66-Hi2WJZOcT2WIGjL2ka1spYVq0WNoRJCNVxrbNJqSWsNrVJSul7KlrfAO12xlldNqzsQx8XpXnc7tQN0DsKY7MZskx9s-m6i9eZhJvi1WcVrw2jFpWAVKpzcKaT4dYI8msFnh63bAHHKRjAllOZUi_-ivKEcN4QrQPT1H-hVnFLAUewoRWsp1IFa2Q0YnGjEf3S3omZR4U4rJCVS879QeDoYvIsBeo_fHxTwfYFLMecE_f08GDW3FjN7ixm0mNlZzNRY9Or3Sd6X_PIUAmIPZEyFFaRDS_-QvQHvwNnu</recordid><startdate>20240101</startdate><enddate>20240101</enddate><creator>Sapp, Sarah G. H.</creator><creator>Low, Ross</creator><creator>Nine, Gabriela</creator><creator>Nascimento, Fernanda S.</creator><creator>Qvarnstrom, Yvonne</creator><creator>Barratt, Joel L. N.</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><scope>5PM</scope></search><sort><creationdate>20240101</creationdate><title>Genetic characterization and description of Leishmania (Leishmania) ellisi sp. nov.: a new human-infecting species from the USA</title><author>Sapp, Sarah G. H. ; Low, Ross ; Nine, Gabriela ; Nascimento, Fernanda S. ; Qvarnstrom, Yvonne ; Barratt, Joel L. 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H.</creatorcontrib><creatorcontrib>Low, Ross</creatorcontrib><creatorcontrib>Nine, Gabriela</creatorcontrib><creatorcontrib>Nascimento, Fernanda S.</creatorcontrib><creatorcontrib>Qvarnstrom, Yvonne</creatorcontrib><creatorcontrib>Barratt, Joel L. N.</creatorcontrib><collection>Springer Nature OA/Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Parasitology research (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sapp, Sarah G. H.</au><au>Low, Ross</au><au>Nine, Gabriela</au><au>Nascimento, Fernanda S.</au><au>Qvarnstrom, Yvonne</au><au>Barratt, Joel L. N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genetic characterization and description of Leishmania (Leishmania) ellisi sp. nov.: a new human-infecting species from the USA</atitle><jtitle>Parasitology research (1987)</jtitle><stitle>Parasitol Res</stitle><addtitle>Parasitol Res</addtitle><date>2024-01-01</date><risdate>2024</risdate><volume>123</volume><issue>1</issue><spage>52</spage><epage>52</epage><pages>52-52</pages><artnum>52</artnum><issn>0932-0113</issn><issn>1432-1955</issn><eissn>1432-1955</eissn><abstract>In a 2018 report, an unusual case of cutaneous leishmaniasis was described in a 72-year-old female patient residing in Arizona, United States of America (USA). Preliminary analysis of the 18S rDNA and glyceraldehyde-3-phosphate dehydrogenase genes supported the conclusion that the
Leishmania
strain (strain 218-L139) isolated from this case was a novel species, though a complete taxonomic description was not provided. Identification of
Leishmania
at the species level is critical for clinical management and epidemiologic investigations so it is important that novel human-infecting species are characterized taxonomically and assigned a unique scientific name compliant with the ICZN code. Therefore, we sought to provide a complete taxonomic description of
Leishmania
strain 218-L139. Phylogenetic analysis of several nuclear loci and partial maxicircle genome sequences supported its position within the subgenus
Leishmania
and further clarified the distinctness of this new species. Morphological characterization of cultured promastigotes and amastigotes from the original case material is also provided. Thus, we conclude that
Leishmania
(
Leishmania
)
ellisi
is a new cause of autochthonous cutaneous leishmaniasis in the USA.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>38099974</pmid><doi>10.1007/s00436-023-08034-8</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0932-0113 |
| ispartof | Parasitology research (1987), 2024-01, Vol.123 (1), p.52-52, Article 52 |
| issn | 0932-0113 1432-1955 1432-1955 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10724317 |
| source | SpringerLink Journals - AutoHoldings |
| subjects | Amastigotes Arizona Biomedical and Life Sciences Biomedicine Cutaneous leishmaniasis Epidemiology females Genetic aspects genome Genomes Genomics Glyceraldehyde-3-phosphate dehydrogenase Immunology Leishmania Leishmaniasis Medical Microbiology Microbiology New species Parasitic diseases patients Phosphates Phylogeny Promastigotes species subgenus taxon descriptions Taxonomy |
| title | Genetic characterization and description of Leishmania (Leishmania) ellisi sp. nov.: a new human-infecting species from the USA |
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