Durability of single-dose HPV vaccination in young Kenyan women: randomized controlled trial 3-year results

Cervical cancer burden is high where prophylactic vaccination and screening coverage are low. We demonstrated in a multicenter randomized, double-blind, controlled trial that single-dose human papillomavirus (HPV) vaccination had high vaccine efficacy (VE) against persistent infection at 18 months i...

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Veröffentlicht in:	Nature medicine 2023-12, Vol.29 (12), p.3224-3232
Hauptverfasser:	Barnabas, Ruanne V., Brown, Elizabeth R., Onono, Maricianah A., Bukusi, Elizabeth A., Njoroge, Betty, Winer, Rachel L., Galloway, Denise A., Pinder, Leeya F., Donnell, Deborah, N. Wakhungu, Imelda, Biwott, Charlene, Kimanthi, Syovata, Heller, Kate B., Kanjilal, Diane G., Pacella, Daniel, Morrison, Susan, A. Rechkina, Elena, L. Cherne, Stephen, Schaafsma, Torin T., McClelland, R. Scott, Celum, Connie, Baeten, Jared M., Mugo, Nelly R.
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308/575 692/700/459/1748 Biomedical and Life Sciences Biomedicine Cancer Research Cervical cancer Double-Blind Method Durability Female Human papillomavirus Human papillomavirus 16 Human papillomavirus 18 Humans Immunization Infections Infectious Diseases Kenya - epidemiology Metabolic Diseases Molecular Medicine Neurosciences Papillomaviridae Papillomavirus Infections - prevention & control Papillomavirus Vaccines - adverse effects Persistent Infection Uterine Cervical Neoplasms - prevention & control Vaccination - methods Vaccine efficacy Vaccines
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