Sicilian semi- and supercentenarians: identification of age-related T-cell immunophenotype to define longevity trait

Abstract The immunophenotype of oldest centenarians, i.e. semi- and supercentenarians, could provide important information about their ability to adapt to factors associated with immune changes, including ageing per se and chronic Cytomegalovirus infection. We investigated, by flow cytometry, variat...

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Veröffentlicht in:	Clinical and experimental immunology 2023-12, Vol.214 (1), p.61-78
Hauptverfasser:	Ligotti, Mattia Emanuela, Accardi, Giulia, Aiello, Anna, Aprile, Stefano, Calabrò, Anna, Caldarella, Rosalia, Caruso, Calogero, Ciaccio, Marcello, Corsale, Anna Maria, Dieli, Francesco, Di Simone, Marta, Giammanco, Giovanni Maurizio, Mascarella, Chiara, Akbar, Arne N, Meraviglia, Serena, Candore, Giuseppina
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Aging CD8-Positive T-Lymphocytes Centenarians Female Humans Immunity & Ageing Immunosenescence Longevity - genetics Male Middle Aged T-Lymphocytes Young Adult
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