Diabetic Müller-Glial-Cell-Specific Il6ra Knockout Mice Exhibit Accelerated Retinal Functional Decline and Thinning of the Inner Nuclear Layer

PurposeInterleukin-6 (IL-6) is implicated in the pathology of diabetic retinopathy (DR). IL-6 trans-signaling via soluble IL-6 receptor (IL-6R) is primarily responsible for its pro-inflammatory functions, whereas cis-signaling via membrane-bound IL-6R is anti-inflammatory. Using a Müller-glial-cell-...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2023-12, Vol.64 (15), p.1-1
Hauptverfasser:	Glass, Joshua, Robinson, Rebekah L., Greenway, Grace, Jones, Garrett, Sharma, Shruti
Format:	Artikel
Sprache:	eng
Schlagworte:	Retinal Cell Biology
Online-Zugang:	Volltext
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