Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor–BI mediate HDL-initiated signaling

The binding of HDL to scavenger receptor–BI (SR-BI) mediates cholesterol movement. HDL also induces multiple cellular signals, which in endothelium occur through SR-BI and converge to activate eNOS. To determine the molecular basis of a signaling event induced by HDL, we examined the proximal mechan...

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Veröffentlicht in:	The Journal of clinical investigation 2005-03, Vol.115 (4), p.969-977
Hauptverfasser:	Assanasen, Chatchawin, Mineo, Chieko, Seetharam, Divya, Yuhanna, Ivan S., Marcel, Yves L., Connelly, Margery A., Williams, David L., de la Llera-Moya, Margarita, Shaul, Philip W., Silver, David L.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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