MLX plays a key role in lipid and glucose metabolism in humans: Evidence from in vitro and in vivo studies

Enhanced hepatic de novo lipogenesis (DNL) has been proposed as an underlying mechanism for the development of NAFLD and insulin resistance. Max-like protein factor X (MLX) acts as a heterodimer binding partner for glucose sensing transcription factors and inhibition of MLX or downstream targets has...

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Veröffentlicht in:	Metabolism, clinical and experimental clinical and experimental, 2023-07, Vol.144, p.155563-155563, Article 155563
Hauptverfasser:	Nagarajan, Shilpa R., Livingstone, Eilidh J., Monfeuga, Thomas, Lewis, Lara C., Ali, Shahul Hameed Liyakath, Chandran, Anandhakumar, Dearlove, David J., Neville, Matt J., Chen, Lingyan, Maroteau, Cyrielle, Ruby, Maxwell A., Hodson, Leanne
Format:	Artikel
Sprache:	eng
Schlagworte:	DNL Glucose Hepatocytes Human Insulin MLX
Online-Zugang:	Volltext
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