Prevalence of Comorbid Factors in Patients With Recurrent Clostridioides difficile Infection in ECOSPOR III, a Randomized Trial of an Oral Microbiota–Based Therapeutic

Abstract Background Although comorbidities are risk factors for recurrent Clostridioides difficile infection (rCDI), many clinical trials exclude patients with medical conditions such as malignancy or immunosuppression. In a phase 3, double-blind, placebo-controlled, randomized trial (ECOSPOR III),...

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Veröffentlicht in:	Clinical infectious diseases 2023-11, Vol.77 (11), p.1504-1510
Hauptverfasser:	Berenson, Charles S, Lashner, Bret, Korman, Louis Y, Hohmann, Elizabeth, Deshpande, Abhishek, Louie, Thomas J, Sims, Matthew, Pardi, Darrell, Kraft, Colleen S, Wang, Elaine E L, Cohen, Stuart H, Feuerstadt, Paul, Oneto, Caterina, Misra, Bharat, Pullman, John, De, Ananya, Memisoglu, Asli, Lombardi, David A, Hasson, Brooke R, McGovern, Barbara H, von Moltke, Lisa, Lee, Christine H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anti-Bacterial Agents - therapeutic use Clostridioides difficile Clostridium Infections - drug therapy Female Humans Major Male Microbiota Prevalence Recurrence
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